Updated on 2025/07/23

写真b

 
MIYABE Kanji
 
*Items subject to periodic update by Rikkyo University (The rest are reprinted from information registered on researchmap.)
Affiliation*
College of Science Department of Chemistry
Graduate School of Science Doctoral Program in Chemistry
Graduate School of Science Master's Program in Chemistry
Title*
Senior Specially Appointed Professor
Degree
博士（工学） （ 東京大学 ）
Research Interests

  • Chromatography

  • Separation Chemistry

  • Analytical Chemistry

    • Campus Career*
    • 4 2023 - Present 
      College of Science   Department of Chemistry   Senior Specially Appointed Professor
    • 4 2023 - Present 
      Graduate School of Science   Master's Program in Chemistry   Senior Specially Appointed Professor
    • 4 2023 - Present 
      Graduate School of Science   Doctoral Program in Chemistry   Senior Specially Appointed Professor
    • 4 2012 - 3 2023 
      College of Science   Department of Chemistry   Professor
    • 4 2012 - 3 2023 
      Graduate School of Science   Master's Program in Chemistry   Professor
    • 4 2012 - 3 2023 
      Graduate School of Science   Doctoral Program in Chemistry   Professor

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    Research Areas

    • Nanotechnology/Materials / Analytical chemistry

    Research History

    • 4 2012 - Present 
      RIKKYO UNIVERSITY   Graduate School of Science Field of Study: Chemistry   Professor

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    • 4 2012 - Present 
      RIKKYO UNIVERSITY   Graduate School of Science Field of Study: Chemistry   Professor

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    • 4 2012 - Present 
      RIKKYO UNIVERSITY   College of Science Department of Chemistry   Professor

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    • 4 2012 - Present 
      The University of Toyama   Professor Emeritus

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    • 4 2004 - 3 2012 
      University of Toyama   Graduate School of Science and Engineering

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    • 12 2002 - 3 2004 
      Nagoya Institute of Technology   Graduate School of Engineering

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    • 10 1995 - 11 2002 
      University of Toyama

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    • 4 1998 - 8 1999 
      テネシー大学   化学科   博士研究員

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    • 4 1982 - 9 1995 
      栗田工業株式会社   主任研究員

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    • 4 1990 - 3 1992 
      The University of Tokyo   Institute of Industrial Science

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    Education

    • - 3 1982 
      University of Toyama   Graduate School, Division of Natural Science

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      Country： Japan

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    • - 3 1980 
      University of Toyama   Faculty of Liberal Arts and Science (Natural Sciences)

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      Country： Japan

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    Committee Memberships

    • 1 2012 - Present 
      クロマトグラフィー科学会   評議員

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      Committee type：Academic society

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    • 4 2011 - Present 
      日本吸着学会   学会誌編集委員

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      Committee type：Academic society

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    • 4 2003 - Present 
      日本吸着学会   評議員

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      Committee type：Academic society

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    • 4 2011 - 9 2012 
      日本分析化学会   日本分析化学会第61年会実行委員

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      Committee type：Academic society

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    • 4 2007 - 3 2012 
      化学工学会   関西支部北陸地区装置懇話会理事

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      Committee type：Academic society

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    • 1 2008 - 12 2011 
      クロマトグラフィー科学会   学会誌編集委員長

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      Committee type：Academic society

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    • 1 2004 - 12 2011 
      クロマトグラフィー科学会   理事

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      Committee type：Academic society

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    • 4 2010 - 3 2011 
      日本分析化学会   中部支部副支部長

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      Committee type：Academic society

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    • 4 2010 - 3 2011 
      化学工学会   代議員

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      Committee type：Academic society

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    • 4 2008 - 3 2010 
      日本分析化学会   中部支部常任幹事

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      Committee type：Academic society

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    • 4 2007 - 3 2009 
      化学工学会   関西支部幹事

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      Committee type：Academic society

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    • 12 2008 
      クロマトグラフィー科学会   HPLC2008 Kyoto実行委員

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      Committee type：Academic society

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    • 11 2008 
      日本分析化学会   中部支部第18回基礎及び最新の分析化学講習会実行委員長

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      Committee type：Academic society

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    • 4 2006 - 3 2008 
      化学工学会   人材育成センター資格制度試験委員会A委員

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      Committee type：Academic society

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    • 8 2007 
      日本分析化学会   中部支部夏期セミナー実行委員

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      Committee type：Academic society

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    • 5 2007 
      クロマトグラフィー科学会   第14回クロマトグラフィーシンポジウム実行委員長

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      Committee type：Academic society

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    • 1 2002 - 12 2003 
      クロマトグラフィー科学会   評議員

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      Committee type：Academic society

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    • 4 2002 - 9 2002 
      日本分析化学会   中部支部常任幹事

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      Committee type：Academic society

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    • 4 2001 - 3 2002 
      日本分析化学会   中部支部幹事

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      Committee type：Academic society

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    • 8 2000 
      日本分析化学会   中部支部若手交流会実行委員長

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      Committee type：Academic society

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    • 9 1996 
      日本分析化学会   中部支部夏期セミナー実行委員

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      Committee type：Academic society

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    Awards

    • 11 2009  
      クロマトグラフィー科学会  平成21年度クロマトグラフィー科学会学会賞 （モーメント理論に基づくクロマトグラフィー挙動解析法の開発） 
       
      宮部寛志

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      Award type：Award from Japanese society, conference, symposium, etc.  Country：Japan

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    • 5 2000  
      富山県未来財団  平成12年度とやま賞（学術研究部門） （液体クロマトグラフィー系における物質移動機構の解明に関する研究） 
       
      宮部寛志

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      Award type：Award from publisher, newspaper, foundation, etc.  Country：Japan

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    • 1 1997  
      日本分析化学会液体クロマトグラフィー研究懇談会  1997年液体クロマトグラフィー努力賞 （逆相液体クロマト分離系における物質移動現象の解析） 
       
      宮部寛志

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      Award type：Award from Japanese society, conference, symposium, etc.  Country：Japan

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    • 11 1995  
      日本吸着学会  平成7年度日本吸着学会奨励賞 （逆相液体クロマト分離に関する研究） 
       
      宮部寛志

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      Award type：Award from Japanese society, conference, symposium, etc.  Country：Japan

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    Papers

    • Moment analysis of intermolecular interactions between plural solute molecules and one ligand molecule by means of high-performance liquid chromatography

      Kanji Miyabe, Kanoko Hiyama

      Bulletin of the Chemical Society of Japan98 ( 3 )   4 3 2025

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      Publishing type：Research paper (scientific journal)   Publisher：Oxford University Press (OUP)  

      Abstract

      A moment analysis method was developed by combining moment theory and high-performance liquid chromatography (HPLC) to study intermolecular interactions between plural solute molecules and one ligand molecule from the viewpoints of chemical equilibrium and reaction kinetics. The method was applied to the inclusion complex formation between dibenzo-15-crown-5 (DB15C5) and three metal cations, namely Na+, Ca2+, and Ba2+, as concrete examples, to demonstrate the effectiveness of the method. Because the diameter of the metal cations is probably larger than that of the inner cavity of DB15C5, it was assumed that inclusion complexes with a stoichiometry of 2:1 are formed. Elution peak profiles measured using HPLC were analyzed to determine the association equilibrium constant and the association and dissociation rate constants. Their values were correlated with the ratio of the diameter of the metal cation to that of the inner cavity of crown ether. It was indicated that the size consistency between the inner cavity of the crown ether and metal cation is an important factor for the formation of an inclusion complex between them, even when the stoichiometric ratio is 2:1. It was demonstrated that the moment analysis method is effective as an experimental strategy for studying chemical reactions of one ligand molecule with plural solute ones.

      DOI： 10.1093/bulcsj/uoaf024

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      Other Link： https://academic.oup.com/bcsj/article-pdf/98/3/uoaf024/62367130/uoaf024.pdf

    • Moment Analysis of Solute Permeation Kinetics at the Interface of Spherical Molecular Aggregates by Using Partial Supplying High- Performance Liquid Chromatography

      Kanji Miyabe, Yuma Ito

      Industrial & Engineering Chemistry Research64 ( 2 ) 1241 - 1251   31 12 2024

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      Publishing type：Research paper (scientific journal)   Publisher：American Chemical Society (ACS)  

      DOI： 10.1021/acs.iecr.4c03661

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    • Moment analysis by affinity capillary electrophoresis for study of reaction kinetics between phenylboronic acid and monoccharides

      Kanji Miyabe, Mio Oya, Moeko Imaizumi

      Bulletin of the Chemical Society of Japan97 ( 10 )   30 9 2024

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      Publishing type：Research paper (scientific journal)   Publisher：Oxford University Press (OUP)  

      Abstract

      A moment analysis method was applied to study intermolecular interactions between phenylboronic acid and monosaccharides. The values of first absolute and second central moments of elution peaks, measured by affinity capillary electrophoresis (ACE), were analyzed on the basis of the moment theory to determine those of association equilibrium constant and association and dissociation rate constants of the intermolecular interactions. Their values were fairly in agreement with results reported in previous studies. The moment analysis method using ACE has some advantages in comparison with conventional spectroscopic methods. For example, neither immobilization nor fluorescence labelling of solute and/or ligand molecules is required when ACE data are measured. Because the principles of the method are different from those of ordinary spectroscopic ones, this method contributes to the kinetic study of intermolecular interactions from various perspectives. A comparison was made between intrinsic characteristics of the moment analysis method and those of two historical ones developed by the Whitesides and Krylov groups. Some restrictive features of the moment analysis method were also explained. It is concluded that the moment analysis method using ACE is effective as one experimental method for the analysis of intermolecular interactions.

      DOI： 10.1093/bulcsj/uoae104

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      Other Link： https://academic.oup.com/bcsj/article-pdf/97/10/uoae104/60198019/uoae104.pdf

    • Moment analysis method for the determination of permeation kinetics of coumarin at lipid bilayers of liposomes by using capillary electrophoresis

      Kanji Miyabe, Mio Sakai, Shunta Inaba

      ELECTROPHORESIS45 ( 21-22 ) 1885 - 1894   27 9 2024

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      Publishing type：Research paper (scientific journal)   Publisher：Wiley  

      Abstract

      A method was developed for studying mass transfer kinetics at lipid bilayers of liposomes. Elution peaks of coumarin were measured by liposome electrokinetic chromatography (LEKC). Four types of phospholipids having different alkyl chains were used for preparing liposomes, which were used as pseudo‐stationary phases in LEKC systems. Rate constants of permeation across lipid bilayers of liposomes or of adsorption at lipid membranes were determined by analyzing the first absolute and second central moments of the elution peaks measured by LEKC. The rate constants of permeation or adsorption tend to decrease with an increase in the carbon number of the alkyl chains of phospholipids. It was demonstrated that the moment analysis of elution peak profiles measured by LEKC is effective for determining lipid membrane permeability or adsorption kinetics. Compared with other conventional techniques, the method has some advantages for studying mass transfer kinetics at lipid bilayers. Solute permeation across or solute adsorption at real lipid bilayers of liposomes is analyzed. The principle of the method is the analysis of separation behavior in LEKC, which is different from that of the other ones. It is expected that the method contributes to the kinetic study of mass transfer at lipid bilayers from various perspectives.

      DOI： 10.1002/elps.202400100

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    • Moment analysis method for determination of rate constants of solute permeation across interface of spherical molecular aggregates by means of high-performance liquid chromatography

      Kanji Miyabe, Yuma Ito

      Journal of Chromatography A1730   465160 - 465160   8 2024

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      Publishing type：Research paper (scientific journal)   Publisher：Elsevier BV  

      DOI： 10.1016/j.chroma.2024.465160

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    • Moment Analysis Method for Measurement of Reaction Equilibrium and Rate Constants by Using High-Performance Liquid Chromatography

      Kanji Miyabe, Amane Ishitobi, Kanoko Hiyama, Fuzuki Kubotani

      Analytical Chemistry96 ( 11 ) 4553 - 4561   8 3 2024

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      Publishing type：Research paper (scientific journal)   Publisher：American Chemical Society (ACS)  

      DOI： 10.1021/acs.analchem.3c05387

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    • Analysis of Mass Transfer Kinetics at Lipid Bilayer Membranes of Liposome by Means of Electrokinetic Chromatography and Moment Theory

      Kanji Miyabe, Momoko Umeda, Shunta Inaba, Shiori Senoo

      Industrial & Engineering Chemistry Research63 ( 6 ) 2822 - 2830   31 1 2024

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      Publishing type：Research paper (scientific journal)   Publisher：American Chemical Society (ACS)  

      DOI： 10.1021/acs.iecr.3c03848

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    • A study on attempt for determination of permeation kinetics of coumarin at lipid bilayer of liposomes by using capillary electrophoresis with moment analysis theory

      Kanji Miyabe, Shunta Inaba, Momoko Umeda

      Journal of Chromatography A1687   463691 - 463691   1 2023

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      Publishing type：Research paper (scientific journal)   Publisher：Elsevier BV  

      DOI： 10.1016/j.chroma.2022.463691

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    • Moment Analysis of Solute Permeation Kinetics at an Interface of Mixed Micelles of Anionic and Nonionic Surfactants

      Kanji Miyabe, Kayoko Aoki

      Bulletin of the Chemical Society of Japan95 ( 12 ) 1715 - 1722   9 11 2022

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      Publishing type：Research paper (scientific journal)   Publisher：Oxford University Press (OUP)  

      Abstract

      Solubilization phenomena of neutral solutes into mixed micelles of anionic and nonionic surfactants were studied by means of micellar electrokinetic chromatography (MEKC). MEKC experiments were conducted by using mixed micelles consisting of sodium dodecylsulfate (SDS) and polyoxyethylene sorbitan monolaurate (Tween 20) or monostearate (Tween 60) as pseudo-stationary phases while changing the concentration of SDS-Tween mixed micelles and the molar fraction of Tween 20 or 60 in mixed micelles. Elution peak profiles measured by MEKC were analyzed on the basis of the moment theory to determine the solute partition equilibrium constant (Kp) and the rate constants of solute permeation at the interface of mixed micelles (kin and kout). It seems that the values of Kp, kin, and kout are increased by adding Tween 20 or 60 and that the influence of the addition of Tween 60 on their values is more remarkable than that of Tween 20. It was demonstrated that moment analysis of MEKC data is effective for studying solubilization phenomena of surfactant micelles under the conditions that both immobilization and chemical modification (i.e., fluorescence labeling) of solute and micelles are not required.

      DOI： 10.1246/bcsj.20220251

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    • Moment theory of affinity capillary electrophoresis for analysis of reaction kinetics of intermolecular interactions

      Kanji Miyabe

      Journal of Chromatography A1684   463557 - 463557   11 2022

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      Publishing type：Research paper (scientific journal)   Publisher：Elsevier BV  

      DOI： 10.1016/j.chroma.2022.463557

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    • Moment equations for partial filling capillary electrophoresis

      Kanji Miyabe

      ELECTROPHORESIS43 ( 4 ) 559 - 570   6 12 2021

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      Publishing type：Research paper (scientific journal)   Publisher：Wiley  

      Abstract

      Moment equations were developed for partial filling CE systems, in which solute dissolution phenomena by spherical molecular assemblies or intermolecular interactions take place. Because experimental conditions of partial filling CE are divided into five categories on the basis of the magnitude relationship between the migration velocity of solute molecules and that of molecular assemblies or ligand molecules, the moment equations were systematically developed for each case by using the Einstein equation for diffusion and the random walk model. In order to demonstrate the effectiveness of the moment equations, they were applied to the analysis of partial filling CE behavior, which is correlated with dissolution phenomena of small solute molecules into spherical molecular assemblies as specific examples. Simulation results only in the case that the migration velocity of solute molecules is faster than that of molecular assemblies were represented in this paper. Detailed explanations about the derivation procedure of the moment equations and the simulation results in other cases can be found in the Supporting Information. The moment equations are theoretical bases for applying partial filling CE to the study on solute permeation kinetics at the interface of spherical molecular assemblies and on reaction kinetics of intermolecular interactions.

      DOI： 10.1002/elps.202100293

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      Other Link： https://onlinelibrary.wiley.com/doi/full-xml/10.1002/elps.202100293

    • Kinetic study on solute permeation at the interface of molecular aggregates by partial filling capillary electrophoresis

      Kanji Miyabe, Mari Nakajima

      ELECTROPHORESIS42 ( 23 ) 2528 - 2537   5 10 2021

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      Publishing type：Research paper (scientific journal)   Publisher：Wiley  

      Abstract

      Moment analysis method using partial filling CE was developed for the kinetic study on solute permeation at the interface of spherical molecular aggregates. Moment equations for partial filling CE were developed by classifying CE systems into five categories according to the migration velocities of solute and molecular aggregate. The method was applied to the study on the dissolution of electrically neutral solutes into SDS micelles. Elution peaks were measured by partial filling CE while changing the concentration of SDS and the filling ratio of SDS micellar zone to the capillary (ϕ<sub>M</sub>). Partition equilibrium constants (K<sub>p</sub>) and rate constants of interfacial solute permeation of SDS micelles (k<sub>in</sub> and k<sub>out</sub>) were determined from the first absolute and second central moments of the elution peaks by using the moment equations. Their values were comparable irrespective of ϕ<sub>M</sub> and were almost the same as those previously measured by complete filling CE. The positive correlation of K<sub>p</sub> with the hydrophobicity of the solutes was explained in terms of the change in k<sub>in</sub> and k<sub>out</sub>. It was demonstrated that the moment analysis method using partial filling CE is effective for studying solute permeation kinetics at the interface of spherical molecular aggregates.

      DOI： 10.1002/elps.202100252

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      Other Link： https://onlinelibrary.wiley.com/doi/full-xml/10.1002/elps.202100252

    • Moment Theory of Chromatography for the Analysis of Reaction Kinetics of Intermolecular Interactions

      Kanji Miyabe, Ayaka Arai, Mana Ishizuka

      Analytical Chemistry93 ( 29 ) 10365 - 10371   14 7 2021

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      Publishing type：Research paper (scientific journal)   Publisher：American Chemical Society (ACS)  

      DOI： 10.1021/acs.analchem.1c02111

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    • Simplification of Moment Analysis Procedure for Kinetic Study of Chromatographic Behavior of Core-shell Particles

      Kanji Miyabe

      Analytical Sciences37 ( 11 ) 1553 - 1557   30 4 2021

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      Publishing type：Research paper (scientific journal)   Publisher：Springer Science and Business Media LLC  

      DOI： 10.2116/analsci.21p094

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      Other Link： https://link.springer.com/article/10.2116/analsci.21P094/fulltext.html

    • Moment Equations for Kinetic Study of Intermolecular Interaction by Size Exclusion Chromatography

      Kanji Miyabe

      Bulletin of the Chemical Society of Japan94 ( 3 ) 755 - 761   12 12 2020

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      Publishing type：Research paper (scientific journal)   Publisher：Oxford University Press (OUP)  

      Abstract

      New moment equations were developed for size exclusion chromatography (SEC), in which chemical reactions simultaneously take place. It is expected that accurate information about affinity kinetics of intermolecular interactions with no immobilization and no chemical modification of solute and ligand molecules can be obtained from elution peak profiles measured by SEC. Moment equations for the first absolute (μ1A) and second central (μ2C) moment of elution peaks were developed on the basis of the Einstein equation for diffusion and the random walk model in order to analytically determine association (ka) and dissociation (kd) rate constant of intermolecular interactions. They were used to predict chromatographic behavior in hypothetical SEC systems to demonstrate their effectiveness. The influence of some parameters on μ1A and μ2C of elution peaks measured in the SEC systems was quantitatively evaluated. It was indicated that the contributions of axial dispersion and reaction kinetics to μ2C depend on some SEC conditions. It is important to control the SEC conditions so that the reaction kinetics has a predominant contribution to μ2C to determine accurate values of ka and kd. The moment equations are effective for optimizing experimental conditions to accurately analyze intermolecular interactions from kinetic points of view.

      DOI： 10.1246/bcsj.20200315

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    • Simple Moment Analysis for a Kinetic Study of the Chromatographic Behavior of Spherical Particles and Silica Monoliths

      Kanji Miyabe

      Analytical Sciences37 ( 4 ) 593 - 598   9 10 2020

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      Publishing type：Research paper (scientific journal)   Publisher：Springer Science and Business Media LLC  

      DOI： 10.2116/analsci.20p331

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      Other Link： https://link.springer.com/article/10.2116/analsci.20P331/fulltext.html

    • Moment analysis of peak broadening in affinity capillary electrophoresis and electrokinetic chromatography

      Kanji Miyabe

      Journal of Chromatography A1609   460451 - 460451   1 2020

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      Publishing type：Research paper (scientific journal)   Publisher：Elsevier BV  

      DOI： 10.1016/j.chroma.2019.460451

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    • Moment theory for the analytical determination of rate constants for solute permeation at the interface of spherical molecular aggregates

      Kanji Miyabe, Shiori Senoo, Nanami Okayasu

      ELECTROPHORESIS40 ( 22 ) 2962 - 2970   18 9 2019

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      Publishing type：Research paper (scientific journal)   Publisher：Wiley  

      Abstract

      Moment equations were developed on the basis of the Einstein equation for diffusion and the random walk model to analytically determine the rate constant for the interfacial solute permeation from a bulk solvent into molecular aggregates (k<sub>in</sub>) and the inverse rate constant from the molecular aggregates to the bulk solvent (k<sub>out</sub>). The moment equations were in good agreement with those derived in a different manner. To demonstrate their effectiveness in one concrete example, the moment equations were used to analytically determine the values of k<sub>in</sub> and k<sub>out</sub> of three electrically neutral solutes, i.e. resorcinol, phenol, and nitrobenzene, from the first absolute (μ<sub>1A</sub>) and second central (μ<sub>2C</sub>) moments of their elution peaks, as measured by electrokinetic chromatography (EKC), in which the sodium dodecyl sulfate (SDS) micelles were used as a pseudostationary phase. The values of k<sub>in</sub> and k<sub>out</sub> should be determined with no chemical modifications and no physical action with the molecular aggregates because they are dynamic systems formed through weak interactions between the components. The moment analysis of the elution peak profiles measured by EKC is effective to unambiguously determine k<sub>in</sub>, k<sub>out</sub>, and the partition equilibrium constant (k<sub>in</sub>/k<sub>out</sub>) under appropriate experimental conditions.

      DOI： 10.1002/elps.201900182

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      Other Link： https://onlinelibrary.wiley.com/doi/full-xml/10.1002/elps.201900182

    • Moment analysis of mass transfer kinetics in micellar electrokinetic chromatography systems Peer-reviewed

      Kanji Miyabe, Nozomu Suzuki

      Analytical Sciences34 ( 2 ) 215 - 220   2018

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      Language：English   Publishing type：Research paper (scientific journal)   Publisher：Japan Society for Analytical Chemistry  

      DOI： 10.2116/analsci.34.215

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    • Numerical Correction for Asymmetrical Peak Profiles for Moment Analysis of Chromatographic Behavior Peer-reviewed

      Miyabe, K

      J. Chromatogr. A1567   155 - 163   2018

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      Language：English   Publishing type：Research paper (scientific journal)  

      DOI： 10.1016/j.chroma.2018.06.067

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    • Moment Analysis for Mass Transfer Kinetics at the Interface of Spherical Molecular Aggregates Peer-reviewed

      Miyabe, K

      J. Chromatogr. A1572   172 - 178   2018

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      Language：English   Publishing type：Research paper (scientific journal)  

      DOI： 10.1016/j.chroma.2018.08.036

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    • Moment Analysis for Reaction Kinetics of Intermolecular Interactions Peer-reviewed

      Miyabe, K

      Electrophoresis39   3032 - 3039   2018

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      Language：English   Publishing type：Research paper (scientific journal)  

      DOI： 10.1002/elps.201800218

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    • Kinetic Study of Chiral Intermolecular Interactions by Moment Analysis Based on Affinity Capillary Electrophoresis Peer-reviewed

      Suzuki, N, Kinoshita, M, Miyabe, K

      Anal. Chem.90   11048 - 11053   2018

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      Language：English   Publishing type：Research paper (scientific journal)  

      DOI： 10.1021/acs.analchem.8b02823

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    • Moment Analysis Theory for Size Exclusion Capillary Electrochromatography with Chemical Reaction of Intermolecular Interaction Peer-reviewed

      Kanji Miyabe, Nozomu Suzuki

      ANALYTICAL SCIENCES33 ( 10 ) 1147 - 1154   10 2017

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      Language：English   Publishing type：Research paper (scientific journal)  

      DOI： 10.2116/analsci.33.1147

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    • Evaluation of Migration Time and Variance for Accurate Kinetic Studies Based on Affinity Capillary Electrophoresis Peer-reviewed

      Nozomu Suzuki, Kanji Miyabe

      ANALYTICAL CHEMISTRY89 ( 19 ) 10487 - 10495   10 2017

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      Language：English   Publishing type：Research paper (scientific journal)  

      DOI： 10.1021/acs.analchem.7b02598

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    • Determination of Association and Dissociation Rate Constants in an Inclusion Complex System between Thymol and Sulfated-beta-cyclodextrin by Moment Analysis - Affinity Capillary Electrophoresis Peer-reviewed

      Kanji Miyabe, Nozomu Suzuki, Youki Shimazaki

      BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN89 ( 10 ) 1219 - 1224   10 2016

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      Language：English   Publishing type：Research paper (scientific journal)  

      DOI： 10.1246/bcsj.20160193

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    • Kinetic Study of Solute Permeation across Surfactant Micelle/Bulk Solvent Interface by Moment Analysis - Chromatographic Capillary Electrophoresis (MA-CCE) Peer-reviewed

      Kanji Miyabe, Nozomu Suzuki

      BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN89 ( 10 ) 1212 - 1218   10 2016

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      Language：English   Publishing type：Research paper (scientific journal)  

      DOI： 10.1246/bcsj.20160185

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    • Moment Analysis Theory for Kinetic Study of Intermolecular Interaction by Affinity Capillary Electrophoresis Peer-reviewed

      Kanji Miyabe, Nozomu Suzuki

      BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN89 ( 7 ) 746 - 753   7 2016

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      Language：English   Publishing type：Research paper (scientific journal)  

      DOI： 10.1246/bcsj.20160068

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    • Moment Analysis of Affinity Kinetics in Inclusion Complex System between Thymol and Sulfated-beta-cyclodextrin by Chromatographic Capillary Electrophoresis (CCE) Peer-reviewed

      Kanji Miyabe, Youki Shimazaki

      BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN88 ( 11 ) 1603 - 1611   11 2015

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      Language：English   Publishing type：Research paper (scientific journal)  

      DOI： 10.1246/bcsj.20150203

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    • Kinetic Study of Interaction between Solute Molecule and Surfactant Micelle Peer-reviewed

      Kanji Miyabe, Ryohei Takahashi, Youki Shimazaki

      ANALYTICAL SCIENCES31 ( 10 ) 1019 - 1025   10 2015

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      DOI： 10.2116/analsci.31.1019

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    • Kinetic Study of the Intermolecular Interaction between 2-Phenoxypropionic Acid and beta-Bromo-cyclodextrin Affixed on the Stationary Phase by Liquid Chromatography Peer-reviewed

      Kanji Miyabe, Satoshi Kamiya

      ANALYTICAL SCIENCES31 ( 8 ) 743 - 749   8 2015

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      DOI： 10.2116/analsci.31.743

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    • Moment equations for chromatography based on Langmuir type reaction kinetics Peer-reviewed

      Kanji Miyabe

      JOURNAL OF CHROMATOGRAPHY A1356   171 - 179   8 2014

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      DOI： 10.1016/j.chroma.2014.06.052

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    • Moment Analysis of Chromatographic Behavior of Separation Media for Fast HPLC Peer-reviewed

      Kanji Miyabe, Yuhi Murata

      ANALYTICAL SCIENCES30 ( 2 ) 277 - 283   2 2014

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      DOI： 10.2116/analsci.30.277

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    • Estimation of Molecular Diffusivity in Liquid Phase Systems on the Basis of the Absolute Rate Theory Peer-reviewed

      Kanji Miyabe, Ryo Isogai

      ANALYTICAL SCIENCES29 ( 4 ) 467 - 472   4 2013

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      DOI： 10.2116/analsci.29.467

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    • Measurement of Pore Diffusivity in Separation Media for High Performance Liquid Chromatography Peer-reviewed

      Kanji Miyabe, Yuko Matsumoto, Nobuho Ando, Yumi Teratani

      ANALYTICAL SCIENCES29 ( 3 ) 315 - 323   3 2013

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      DOI： 10.2116/analsci.29.315

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    • Moment Analysis of Chromatographic Behavior of Superficially Porous Particles Peer-reviewed

      Kanji Miyabe, Kazuhiro Noiri, Kouki Kobayashi

      ANALYTICAL SCIENCES27 ( 11 ) 1097 - 1105   11 2011

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    • Estimation of molecular diffusivity in aqueous solution of acetonitrile by the Wilke-Chang equation Peer-reviewed

      Kanji Miyabe

      JOURNAL OF SEPARATION SCIENCE34 ( 19 ) 2674 - 2679   10 2011

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      DOI： 10.1002/jssc.201100385

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    • Moment Equations for Chromatography Using Superficially Porous Spherical Particles Peer-reviewed

      Kanji Miyabe

      ANALYTICAL SCIENCES27 ( 10 ) 1007 - 1017   10 2011

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    • Estimation of molecular diffusivity in liquid phase systems by the Wilke-Chang equation Peer-reviewed

      Kanji Miyabe, Ryo Isogai

      JOURNAL OF CHROMATOGRAPHY A1218 ( 38 ) 6639 - 6645   9 2011

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      DOI： 10.1016/j.chroma.2011.07.018

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    • Extrathermodynamic Study of Retention Equilibrium in RP-LC Using a C-18-Silica Monolithic Stationary Phase Peer-reviewed

      Kanji Miyabe, Akane Matsushima

      CHROMATOGRAPHIA74 ( 3-4 ) 179 - 187   8 2011

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      Language：English   Publishing type：Research paper (scientific journal)  

      DOI： 10.1007/s10337-011-2062-y

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    • Monolithic silica rod columns for high-efficiency reversed-phase liquid chromatography Peer-reviewed

      Shota Miyazaki, Masakazu Takahashi, Masayoshi Ohira, Hiroyuki Terashima, Kei Morisato, Kazuki Nakanishi, Tohru Ikegami, Kanji Miyabe, Nobuo Tanaka

      JOURNAL OF CHROMATOGRAPHY A1218 ( 15 ) 1988 - 1994   4 2011

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      Language：English   Publishing type：Research paper (scientific journal)  

      DOI： 10.1016/j.chroma.2010.11.032

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    • Numerical Method for the Estimation of Column Radial Heterogeneity and of the Actual Column Efficiency from Tailing Peak Profiles Peer-reviewed

      Kanji Miyabe, Georges Guiochon

      ANALYTICAL CHEMISTRY83 ( 1 ) 182 - 192   1 2011

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      Language：English   Publishing type：Research paper (scientific journal)  

      DOI： 10.1021/ac102195x

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    • External mass transfer in silica monolithic stationary phases Peer-reviewed

      Kanji Miyabe, Nobuho Ando, Takuya Nakamura, Georges Guiochon

      CHEMICAL ENGINEERING SCIENCE65 ( 22 ) 5950 - 5960   11 2010

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      Language：English   Publishing type：Research paper (scientific journal)  

      DOI： 10.1016/j.ces.2010.08.020

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    • Peak parking-moment analysis: A strategy for the measurement of molecular diffusivity in liquid phase Peer-reviewed

      Kanji Miyabe, Jun-ichi Nagai, Georges Guiochon

      CHEMICAL ENGINEERING SCIENCE65 ( 12 ) 3859 - 3864   6 2010

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      DOI： 10.1016/j.ces.2010.03.027

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    • Kinetic study on external mass transfer in high performance liquid chromatography system Peer-reviewed

      Kanji Miyabe, Yuuki Kawaguchi, Georges Guiochon

      JOURNAL OF CHROMATOGRAPHY A1217 ( 18 ) 3053 - 3062   4 2010

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      DOI： 10.1016/j.chroma.2010.02.075

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    • An estimation of the column efficiency made by analyzing tailing peak profiles Peer-reviewed

      Kanji Miyabe, Yuko Matsumoto, Yusuke Niwa, Nobuho Ando, Georges Guiochon

      JOURNAL OF CHROMATOGRAPHY A1216 ( 47 ) 8319 - 8330   11 2009

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      DOI： 10.1016/j.chroma.2009.09.006

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    • Surface Diffusion in C-18-Silica Monolithic Stationary Phase Peer-reviewed

      Kanji Miyabe

      JOURNAL OF CHROMATOGRAPHIC SCIENCE47 ( 6 ) 452 - 458   7 2009

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    • Peak parking method for measurement of molecular diffusivity in liquid phase systems Peer-reviewed

      Kanji Miyabe, Nobuho Ando, Georges Guiochon

      JOURNAL OF CHROMATOGRAPHY A1216 ( 20 ) 4377 - 4382   5 2009

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      DOI： 10.1016/j.chroma.2009.02.058

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    • Peak Parking-Moment Analysis Method for the Measurement of Surface Diffusion Coefficients Peer-reviewed

      Kanji Miyabe, Yuko Matsumoto, Nobuho Ando

      ANALYTICAL SCIENCES25 ( 2 ) 211 - 218   2 2009

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    • Thermodynamic Interpretation of Retention Equilibrium in Reversed-Phase Liquid Chromatography Peer-reviewed

      Kanji Miyabe

      ANALYTICAL SCIENCES25 ( 2 ) 219 - 227   2 2009

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    • Thermodynamic interpretation of retention equilibrium in reversed-phase liquid chromatography Peer-reviewed

      Kanji Miyabe

      Analytical Sciences25 ( 2 ) 219 - 227   2009

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      DOI： 10.2116/analsci.25.219

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    • External mass transfer in high performance liquid chromatography systems Peer-reviewed

      Kanji Miyabe, Motoki Ando, Nobuho Ando, Georges Guiochon

      JOURNAL OF CHROMATOGRAPHY A1210 ( 1 ) 60 - 67   11 2008

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      DOI： 10.1016/j.chroma.2008.09.035

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    • Influence of mobile phase composition on surface diffusion in reversed-phase liquid chromatography Peer-reviewed

      Kanji Miyabe

      JOURNAL OF CHROMATOGRAPHY A1194 ( 2 ) 184 - 191   6 2008

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      DOI： 10.1016/j.chroma.2008.04.054

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    • Evaluation of chromatographic performance of various packing materials having different structural characteristics as stationary phase for fast high performance liquid chromatography by new moment equations Peer-reviewed

      Kanji Miyabe

      JOURNAL OF CHROMATOGRAPHY A1183 ( 1-2 ) 49 - 64   3 2008

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      DOI： 10.1016/j.chroma.2007.12.064

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    • New moment equations for chromatography using various stationary phases of different structural characteristics Peer-reviewed

      Kanji Miyabe

      ANALYTICAL CHEMISTRY79 ( 19 ) 7457 - 7472   10 2007

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    • Surface diffusion in reversed-phase liquid chromatography using silica gel stationary phases of different C-1 and C-18 ligand densities Peer-reviewed

      Kanji Miyabe

      JOURNAL OF CHROMATOGRAPHY A1167 ( 2 ) 161 - 170   10 2007

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      DOI： 10.1016/j.chroma.2007.08.045

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    • Peak parking-moment analysis. A strategy for the study of the mass-transfer kinetics in the stationary phase Peer-reviewed

      Kanji Miyabe, Yuko Matsumoto, Georges Guiochon

      ANALYTICAL CHEMISTRY79 ( 5 ) 1970 - 1982   3 2007

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      Language：English   Publishing type：Research paper (scientific journal)  

      DOI： 10.1021/ac061321h

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    • Surface diffusion in reversed-phase liquid chromatography using silica gels bonded with C-1 and C-18 ligands of different densities Peer-reviewed

      Kanji Miyabe

      TALANTA71 ( 5 ) 1915 - 1925   3 2007

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      DOI： 10.1016/j.talanta.2006.08.020

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    • A kinetic parameter concerning mass transfer in silica monolithic and particulate stationary phases measured by the peak-parking and slow-elution methods Peer-reviewed

      Kanji Miyabe, Hiroshi Kobayashi, Daisuke Tokuda, Nobuo Tanaka

      JOURNAL OF SEPARATION SCIENCE29 ( 16 ) 2452 - 2462   11 2006

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    • Faster axial band dispersion in a monolithic silica column than in a particle-packed column Peer-reviewed

      H Kobayashi, D Tokuda, J Ichimaru, T Ikegami, K Miyabe, N Tanaka

      JOURNAL OF CHROMATOGRAPHY A1109 ( 1 ) 2 - 9   3 2006

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      Language：English   Publishing type：Research paper (scientific journal)  

      DOI： 10.1016/j.chroma.2005.11.053

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    • Extrathermodynamic interpretation of retention equilibria in reversed-phase liquid chromatography using octadecylsilyl-silica gels bonded to C-1 and C-18 ligands of different densities Peer-reviewed

      K Miyabe, G Guiochon

      JOURNAL OF CHROMATOGRAPHY A1099 ( 1-2 ) 136 - 148   12 2005

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      DOI： 10.1016/j.chroma.2005.09.001

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    • Effect of the silanization conditions on chromatographic behavior of an open-tubular capillary column coated with a modified silica-gel thin layer Peer-reviewed

      Y Nakano, S Kitagawa, K Miyabe, T Tsuda

      ANALYTICAL SCIENCES21 ( 10 ) 1167 - 1170   10 2005

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    • Extrathermodynamic study of surface diffusion in reversed-phase liquid chromatography with silica gels bonded with alkyl ligands of different chain lengths Peer-reviewed

      K Miyabe, G Guiochon

      JOURNAL OF PHYSICAL CHEMISTRY B109 ( 24 ) 12038 - 12048   6 2005

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      DOI： 10.1021/jp058028q

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    • Preparation of a new type of fiber adsorbent attached with silica microparticles Peer-reviewed

      T Tsuda, M Hisanaga, T Inagaki, S Kitagawa, K Miyabe

      ANALYTICAL SCIENCES20 ( 7 ) 1061 - 1064   7 2004

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    • Comparison of the characteristics of adsorption equilibrium and surface diffusion in liquid-solid and gas-solid adsorption on C-18-silica gels Peer-reviewed

      K Miyabe, G Guiochon

      JOURNAL OF PHYSICAL CHEMISTRY B108 ( 9 ) 2987 - 2997   3 2004

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      DOI： 10.1021/jp0309421

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    • Moment analysis of mass-transfer kinetics in C-18-silica monolithic columns Peer-reviewed

      K Miyabe, A Cavazzini, F Gritti, M Kele, G Guiochon

      ANALYTICAL CHEMISTRY75 ( 24 ) 6975 - 6986   12 2003

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      DOI： 10.1021/ac0302206

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    • Kinetic study of the hydrodechlorination of trichloroethene in water using a platinum catalyst and hydrazine Peer-reviewed

      K Miyabe, N Taniguchi, A Imura, Y Tezuka

      WATER ENVIRONMENT RESEARCH75 ( 5 ) 472 - 477   9 2003

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    • Moment analysis of retention equilibrium, mass transfer kinetics, and thermodynamic properties in reversed-phase liquid chromatography using phenyl bonded silica gel Peer-reviewed

      K Miyabe, Y Sakai, M Sarashina, C Yokokawa

      ANALYST128 ( 12 ) 1425 - 1433   2003

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      DOI： 10.1039/b308293h

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    • Thermodynamic interpretation of retention equilibrium in reversed-phase liquid chromatography based on enthalpy-entropy compensation Peer-reviewed

      K Miyabe, G Guiochon

      ANALYTICAL CHEMISTRY74 ( 23 ) 5982 - 5992   12 2002

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      DOI： 10.1021/ac0202233

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    • Extrathermodynamic relationships in reversed-phase liquid chromatography Peer-reviewed

      K Miyabe, G Guiochon

      ANALYTICAL CHEMISTRY74 ( 22 ) 5754 - 5765   11 2002

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      DOI： 10.1021/ac020245p

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    • The moment equations of chromatography for monolithic stationary phases Peer-reviewed

      K Miyabe, G Guiochon

      JOURNAL OF PHYSICAL CHEMISTRY B106 ( 34 ) 8898 - 8909   8 2002

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      DOI： 10.1021/jp020555b

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    • New model of surface diffusion in reversed-phase liquid chromatography Peer-reviewed

      K Miyabe, G Guiochon

      JOURNAL OF CHROMATOGRAPHY A961 ( 1 ) 23 - 33   6 2002

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    • Characteristics and mechanism of surface diffusion in reversed-phase liquid chromatography using various alkyl ligand bonded silica gels Peer-reviewed

      K Miyabe

      ANALYTICAL CHEMISTRY74 ( 9 ) 2126 - 2132   5 2002

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      DOI： 10.1021/ac011184i

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    • Analysis of Surface Diffusion in Reversed-Phase Liquid Chromatography Peer-reviewed

      Miyabe, K

      Proceedings of the Seventh International Conference on Fundamentals of Adsorption   93 - 100   1 2002

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    • Retention equilibrium and mass transfer characteristics in reversed-phase liquid chromatography using methanol-water mixtures Peer-reviewed

      K Miyabe, A Okada

      ANALYST127 ( 11 ) 1420 - 1426   2002

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      DOI： 10.1039/b203667n

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    • Chromatographic Behavior of Alkyl Ligands Bonded Silica Gels Peer-reviewed

      Miyabe, K, Guiochon, G

      Anal. Sci.17 Supplement   i209 - i212   12 2001

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    • Correlation between surface diffusion and molecular diffusion in reversed-phase liquid chromatography Peer-reviewed

      K Miyabe, G Guiochon

      JOURNAL OF PHYSICAL CHEMISTRY B105 ( 38 ) 9202 - 9209   9 2001

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    • Analysis of the surface diffusion of alkylbenzenes and p-alkylphenols in reversed phase liquid chromatography using the surface-restricted molecular diffusion model Peer-reviewed

      K Miyabe, G Guiochon

      ANALYTICAL CHEMISTRY73 ( 13 ) 3096 - 3106   7 2001

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    • Retention and mass transfer characteristics in reversed-phase liquid chromatography using a tetrahydrofuran-water solution as the mobile phase Peer-reviewed

      K Miyabe, S Sotoura, G Guiochon

      JOURNAL OF CHROMATOGRAPHY A919 ( 2 ) 231 - 244   6 2001

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    • Degradation Behavior of Injection Molded Biodegradable Polymers in Soil, Aqueous Environments, and an Activated Sludge. Peer-reviewed

      MIZUNO Wataru, MAEDA Yoshiko, KOZIMA Kanako, TAKAMICHI Tomomi, MIYABE Kanji, TAKEUCHI Shigeya

      Kobunshi Kagaku58 ( 2 ) 59 - 65   2 2001

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      Biodegradation behavior of test pieces of some biodegradable polymers formed by injection molding was investigated in soil, aqueous environments, and an activated sludge. The manner of the biodegradation depended on the composition of materials. With regard to the tests in soil and aqueous environments in the field, the degradation progressed during spring and fall. In an activated sludge of a sewage treatment plant, Biopol and Mater-Bi were degraded. The extent of the degradation of Biopol was influenced by the density of microbes. The degradation of Biopol was facilitated in an aeration tank, in which the microbe density was high. It was estimated that about 50 wt% of the biodegradable polymers was degraded in one year in the activated sludge. Waste treatment of polymers in a sewage treatment plant would be one of the effective methods, provided the safety of the treatment is confirmed.

      DOI： 10.1295/koron.58.59

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    • Influence of the modification conditions of alkyl bonded ligands on the characteristics of reversed-phase liquid chromatography Peer-reviewed

      K Miyabe, G Guiochon

      JOURNAL OF CHROMATOGRAPHY A903 ( 1-2 ) 1 - 12   12 2000

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    • A kinetic study of mass transfer in reversed-phase liquid chromatography on a C18-silica gel Peer-reviewed

      K Miyabe, G Guiochon

      ANALYTICAL CHEMISTRY72 ( 21 ) 5162 - 5171   11 2000

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      DOI： 10.1021/ac0002801

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    • Interpretation by the solvophobic theory on the linear additive representation of the logarithm of ion-pair extraction constant with individual contributions of cation, anion, and organic solvent Peer-reviewed

      K Miyabe, S Taguchi, Kasahara, I, K Goto

      JOURNAL OF PHYSICAL CHEMISTRY B104 ( 35 ) 8481 - 8490   9 2000

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      DOI： 10.1021/jp000918c

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    • Influence of the column radial heterogeneity on the determination of single-component isotherms by the elution by characteristic point method Peer-reviewed

      K Miyabe, G Guiochon

      JOURNAL OF CHROMATOGRAPHY A891 ( 2 ) 217 - 233   9 2000

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    • A Study of Mass Transfer Kinetics in an Enantiomeric Separation System Using a Polymeric Imprinted Stationary Phase Peer-reviewed

      Miyabe, K, Guiochon, G

      Biotechnol. Prog.16   617 - 629   8 2000

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    • Determination of the lumped mass transfer rate coefficient by frontal analysis Peer-reviewed

      K Miyabe, G Guiochon

      JOURNAL OF CHROMATOGRAPHY A890 ( 2 ) 211 - 223   8 2000

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    • Kinetic study of the concentration dependence of the mass transfer rate coefficient in enantiomeric separation on a polymeric imprinted stationary phase Peer-reviewed

      K Miyabe, G Guiochon

      ANALYTICAL SCIENCES16 ( 7 ) 719 - 730   7 2000

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    • Restricted diffusion model for surface diffusion in reversed-phase liquid chromatography Peer-reviewed

      K Miyabe, G Guiochon

      ANALYTICAL CHEMISTRY72 ( 7 ) 1475 - 1489   4 2000

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    • Study on the accuracy of the elution by characteristic point method for the determination of single component isotherms Peer-reviewed

      K Miyabe, S Khattabi, DE Cherrak, G Guiochon

      JOURNAL OF CHROMATOGRAPHY A872 ( 1-2 ) 1 - 21   3 2000

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    • Kinetic study of the mass transfer of bovine serum albumin in anion-exchange chromatography Peer-reviewed

      K Miyabe, G Guiochon

      JOURNAL OF CHROMATOGRAPHY A866 ( 2 ) 147 - 171   1 2000

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    • Thermodynamic characteristics of surface diffusion in reversed-phase liquid chromatography Peer-reviewed

      K Miyabe, G Guiochon

      JOURNAL OF PHYSICAL CHEMISTRY B103 ( 50 ) 11086 - 11097   12 1999

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    • Influence of column radial heterogeneity on peak fronting in linear chromatography Peer-reviewed

      K Miyabe, G Guiochon

      JOURNAL OF CHROMATOGRAPHY A857 ( 1-2 ) 69 - 87   10 1999

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    • Kinetic Study of the Concentration Dependence of the Mass Transfer Rate Coefficient in Anion-Exchange Chromatography of Bovine Serum Albumin Peer-reviewed

      Miyabe, K, Guiochon, G

      Biotechnol. Prog.15   740 - 752   8 1999

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    • Kinetic study of the mass transfer of S-Troger's base in the system cellulose triacetate and ethanol Peer-reviewed

      K Miyabe, G Guiochon

      JOURNAL OF CHROMATOGRAPHY A849 ( 2 ) 445 - 465   7 1999

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    • Analysis of surface diffusion phenomena in reversed-phase liquid chromatography Peer-reviewed

      K Miyabe, G Guiochon

      ANALYTICAL CHEMISTRY71 ( 4 ) 889 - 896   2 1999

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    • Adsorption characteristics in reversed-phase liquid chromatography using ethanol water mixed solvent Peer-reviewed

      K Miyabe, S Takeuchi, Y Tezuka

      ADSORPTION-JOURNAL OF THE INTERNATIONAL ADSORPTION SOCIETY5 ( 1 ) 15 - 24   1 1999

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    • Estimation of the column radial heterogeneity from an analysis of the characteristics of tailing peaks in linear chromatography Peer-reviewed

      K Miyabe, G Guiochon

      JOURNAL OF CHROMATOGRAPHY A830 ( 1 ) 29 - 39   1 1999

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    • Peak tailing and column radial heterogeneity in linear chromatography Peer-reviewed

      K Miyabe, G Guiochon

      JOURNAL OF CHROMATOGRAPHY A830 ( 2 ) 263 - 274   1 1999

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    • Estimation of surface diffusion coefficient in liquid phase adsorption Peer-reviewed

      K Miyabe, S Takeuchi

      CANADIAN JOURNAL OF CHEMICAL ENGINEERING76 ( 5 ) 887 - 892   10 1998

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    • Estimation of the surface-diffusion coefficient in gas-phase adsorption using octadecylsilyl-silica gel Peer-reviewed

      K Miyabe, S Takeuchi, Y Tezuka

      BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN71 ( 8 ) 1755 - 1761   8 1998

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    • Estimation of surface diffusion coefficient in reversed-phase liquid chromatography using methanol/water mobile phases Peer-reviewed

      K Miyabe, S Takeuchi, Y Tezuka

      JOURNAL OF CHEMICAL ENGINEERING OF JAPAN31 ( 3 ) 347 - 354   6 1998

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    • Retention behavior of p-alkylphenols in reversed-phase liquid chromatography using ethanol/water mixtures Peer-reviewed

      K Miyabe, N Nomura, F Morishita, S Kurata, H Asamura, Y Imada

      ANALYTICAL SCIENCES14 ( 2 ) 355 - 359   4 1998

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    • Effect of the type of organic modifiers on mass transfer in reversed-phase liquid chromatography Peer-reviewed

      K Miyabe, S Takeuchi

      ANALYTICAL SCIENCES14 ( 2 ) 361 - 368   4 1998

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    • Surface diffusion of alkylbenzenes on octadecylsilyl-silica gel Peer-reviewed

      K Miyabe, S Takeuchi

      INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH37 ( 3 ) 1154 - 1158   3 1998

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    • The Reaction of Hydrogen and Dinitrogen Monoxide over Silver Catalyst : Studies on the Catalytic Reactions of the Toxic Substances(2) Peer-reviewed

      TEZUKA Yoshisato, MIYABE Kanji

      Memoirs of the Faculty of Education, Toyama University. Series B52   19 - 23   2 1998

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    • Adsorption characteristics in reversed-phase liquid chromatography using methanol/water and acetonitrile/water mobile phases Peer-reviewed

      K Miyabe, S Takeuchi

      JOURNAL OF CHEMICAL ENGINEERING OF JAPAN30 ( 6 ) 1047 - 1053   12 1997

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    • Model for surface diffusion in liquid-phase adsorption Peer-reviewed

      K Miyabe, S Takeuchi

      AICHE JOURNAL43 ( 11 ) 2997 - 3006   11 1997

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    • Analysis of peak spreading phenomena in liquid chromatography Peer-reviewed

      K Miyabe, S Takeuchi

      ANALYTICAL SCIENCES13 ( 5 ) 713 - 720   10 1997

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    • Surface diffusion phenomena in reversed-phase liquid chromatography with methanol/water and acetonitrile/water mixtures Peer-reviewed

      K Miyabe, S Takeuchi

      INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH36 ( 10 ) 4335 - 4341   10 1997

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    • Analysis of surface diffusion phenomena in liquid phase adsorption Peer-reviewed

      K Miyabe, S Takeuchi

      JOURNAL OF PHYSICAL CHEMISTRY B101 ( 39 ) 7773 - 7779   9 1997

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    • Numerical Analysis of Height Equivalent to a Theoretical Plate in Reversed-Phase Liquid Chromatography Peer-reviewed

      Miyabe, K, Takeuchi, S

      CHROMATOGRAPHY18   161 - 168   7 1997

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    • Effect of acetonitrile/water mobile-phase composition on adsorption characteristics of reversed-phase liquid chromatography Peer-reviewed

      K Miyabe, S Takeuchi

      ANALYTICAL CHEMISTRY69 ( 13 ) 2567 - 2574   7 1997

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    • Mass-transfer properties of reversed-phase portion LC with an acetonitrile-water mobile phase Peer-reviewed

      MIYABE Kanji, RENZO Yuji, TAKEUCHI Shigeya

      BUNSEKI KAGAKU46 ( 7 ) 579 - 586   7 1997

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      Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：The Japan Society for Analytical Chemistry  

      The adsorption characteristics of reversed-phase liquid chromatography were studied by the chromatographic method and a moment analysis. Octadecylsilyl-silica gel was used as a stationary phase and an acetonitrile-water (70/30,v/v) mixture as a mobile phase. The equilibrium, kinetic, and thermodynamic properties of adsorption phenomena in the system were elucidated, and compared with those in a reversed-phase system using a methanol-water (70/30,v/v) mixed solvent as a mobile phase. The magnitude of the interaction between the adsorbate molecules and octadecyl ligands in 70 vol% acetonitrile was weaker than that in 70 vol% methanol. In both adsorption systems, the surface diffusion was dominant for intraparticle diffusion. Surface diffusion phenomena were considered from the viewpoint of the thermodynamic properties. The establishment of an enthalpy-entropy compensation effect was confirmed for surface diffusion phenomena. The differences in the mass-transfer properties in both reversed-phase liquid chromatographic systems were quantitatively elucidated from equilibrium, kinetic, and thermodynamic points of view

      DOI： 10.2116/bunsekikagaku.46.579

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      Other Link： http://dl.ndl.go.jp/info:ndljp/pid/10894093

    • SOLVENT EFFECT ON ADSORPTION PHENOMENA IN REVERSED-PHASE LIQUID-CHROMATOGRAPHY Peer-reviewed

      K MIYABE, M SUZUKI

      AICHE JOURNAL41 ( 3 ) 536 - 547   3 1995

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    • CHROMATOGRAPHIC STUDY ON LIQUID-PHASE ADSORPTION ON OCTADECYLSILYL-SILICA GEL Peer-reviewed

      K MIYABE, M SUZUKI

      AICHE JOURNAL41 ( 3 ) 548 - 558   3 1995

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    • ADSORPTION CHARACTERISTICS OF REVERSED-PHASE LIQUID-CHROMATOGRAPHY WITH VARIOUS ALKYL BONDED PHASES Peer-reviewed

      K MIYABE, M SUZUKI

      JOURNAL OF CHEMICAL ENGINEERING OF JAPAN27 ( 6 ) 785 - 789   12 1994

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    • MASS-TRANSFER PHENOMENA ON THE SURFACE OF ADSORBENTS IN REVERSED-PHASE CHROMATOGRAPHY Peer-reviewed

      K MIYABE, M SUZUKI

      INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH33 ( 7 ) 1792 - 1802   7 1994

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    • ESTIMATION OF ADSORPTION PARAMETERS OF A BINARY-SYSTEM BY APPLYING THE LEWIS RULE Peer-reviewed

      K MIYABE, M SUZUKI

      JOURNAL OF CHEMICAL ENGINEERING OF JAPAN27 ( 2 ) 257 - 259   4 1994

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    • ADSORPTION CHARACTERISTICS OF OCTADECYLSILYL-SILICA GEL IN GASEOUS SYSTEMS Peer-reviewed

      K MIYABE, M SUZUKI

      AICHE JOURNAL39 ( 11 ) 1791 - 1798   11 1993

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    • 逆相液体クロマト分離の化学工学的研究

      宮部寛志

          18 3 1993

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    • Chromatographic Study of Liquid Phase Adsorption of p-Tert-Octylphenol on Octadecylsilyl-Silica Gel Peer-reviewed

      Kanji Miyabe, Motoyuki Suzuki

      Studies in Surface Science and Catalysis80 ( C ) 437 - 444   1 1 1993

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      Language：English   Publishing type：Research paper (scientific journal)  

      DOI： 10.1016/S0167-2991(08)63545-4

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    • CHROMATOGRAPHY OF LIQUID-PHASE ADSORPTION ON OCTADECYLSILYL-SILICA GEL Peer-reviewed

      K MIYABE, M SUZUKI

      AICHE JOURNAL38 ( 6 ) 901 - 910   6 1992

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    • ESTIMATION OF AN ADSORPTION-ISOTHERM BY ANALYZING A DESORPTION CURVE Peer-reviewed

      K MIYABE, M SUZUKI

      JOURNAL OF CHEMICAL ENGINEERING OF JAPAN24 ( 6 ) 772 - 777   12 1991

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    • DETERMINATION AND CHARACTERIZATION OF REVERSED-PHASE BONDED LIGANDS BY CHEMICAL CLEAVAGE WITH AQUEOUS HYDROFLUORIC-ACID Peer-reviewed

      K MIYABE, N ORITA

      TALANTA36 ( 9 ) 897 - 902   9 1989

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    • Industrial-scale reversed-phase liquid chromatography with a multicolumn system. Peer-reviewed

      Miyabe Kanji, Kawazoe Tetsuya, Yamaguchi Masato, Kitazawa Kouji

      Chemical engineering15 ( 3 ) 475 - 480   5 1989

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      Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：The Society of Chemical Engineers, Japan  

      An industrial-scale reversed-phase liquid chromatograph was developed by using a multicolumn system. Its use reduced the volume of solvent and the operation time for chromatography, to about one -tenth of those required in a conventional elution. As a result, the maximum concentration of the objective component increased approximately fifteen times.<BR>A simulation method was used to optimize the operational conditions of the column system. The validity of the calculated result was confirmed experimentally.<BR>In industrial-scale liquid chromatography the multicolumn system effectively increases the efficiency of the whole purification process.

      DOI： 10.1252/kakoronbunshu.15.475

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    • Division of ion-pair extraction constants into individual ions and solvents ; Ferron-cationic surfactants system. Peer-reviewed

      GOTO Katsumi, TAGUCHI Shigeru, MIYABE Kanji, HARUYAMA Ken-ichi

      BUNSEKI KAGAKU32 ( 11 ) 678 - 682   11 1983

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      Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：The Japan Society for Analytical Chemistry  

      It is found that the extraction constant K_<ex>, for the ion-pair extraction systems is made up of three independent constants (individual extraction constants), K_e, K_a, and K_s in accordance with the equation: log K_<ex>= log K_c + log K_a + log K_s……………(1) where the subscripts c, a, and s denote cation, anion, and solvent, respectively. The anion, cations, and solvents studied were 7-iodo-8-quinolinol-5-sulfonic acid (ferron), eight cationic surfactants and 1,2-dichloroethane, dichloromethane, and chloroform. Cationic surfactants used in this work are alkyltrimethylammonium salts with alkyl chain lengths from 10 to 18 methylene groups, and several quaternary ammonium salts. Logarithm K values for several cations, anion, and solvents were calculated from experimental values of log K_<ex> by tentatively assigning the log K values 1.0 and 1.0 to ferron and chloroform, respectively, as reference value. It was also shown that the association constant, K_A and the distribution constant, KD are made up of independent constants K_<A,c>, K_<A,a>, (individual association constants) and K_<D,c>, K_<D,a>, K_s (individual distribution constants) , respectively, in accordance with the equations: log K_A = log K_<A,c> + log K_<A,a>…………………(2) log K_D=log K_<D,c>+log K_<D,a>+log K_s………(3) where subscript c, a, and s have the same meaning as in equation (1). Experimental data, are presented to show the validity of the above three equations.

      DOI： 10.2116/bunsekikagaku.32.11_678

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      Other Link： http://dl.ndl.go.jp/info:ndljp/pid/10890346

    • EFFECT OF CATIONIC SURFACTANT ON THE FORMATION OF FERRON COMPLEXES Peer-reviewed

      K GOTO, S TAGUCHI, K MIYABE, K HARUYAMA

      TALANTA29 ( 7 ) 569 - 575   1982

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    Misc.

    • Moment theory for kinetic study of chromatography Invited Peer-reviewed

      Kanji Miyabe

      TRAC-TRENDS IN ANALYTICAL CHEMISTRY81   79 - 86   7 2016

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      Language：English   Publishing type：Book review, literature introduction, etc.  

      DOI： 10.1016/j.trac.2016.01.003

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    • Surface diffusion in reversed-phase liquid chromatography

      Kanji Miyabe, Georges Guiochon

      JOURNAL OF CHROMATOGRAPHY A1217 ( 11 ) 1713 - 1734   3 2010

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      DOI： 10.1016/j.chroma.2009.12.054

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    • Development of New Strategy for Analysis of Chromatographic Behavior on the Basis of Moment Theory

      Miyabe, K

      CHROMATOGRAPHY31   1 - 15   3 2010

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      Language：English   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)   Publisher：クロマトグラフィー科学会  

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    • クロマトグラフィー技術開発の二面性

      宮部寛志

      LC talk72   2   4 2009

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      Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Publisher：株式会社 島津製作所  

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    • Moment analysis of chromatographic behavior in reversed-phase liquid chromatography

      Kanji Miyabe

      JOURNAL OF SEPARATION SCIENCE32 ( 5-6 ) 757 - 770   3 2009

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      DOI： 10.1002/jssc.200800607

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    • 外表面多孔性球状粒子分離剤を用いる高性能高速液体クロマトグラフィー

      宮部寛志

      ぶんせき ( 1 ) 30 - 31   1 2009

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      Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (other)   Publisher：日本分析化学会  

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    • Characterization of monolithic columns for HPLC

      K Miyabe, G Guiochon

      JOURNAL OF SEPARATION SCIENCE27 ( 10-11 ) 853 - 873   7 2004

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      DOI： 10.1002/jssc.200401772

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    • Measurement of the parameters of the mass transfer kinetics in high performance liquid chromatography

      K Miyabe, G Guiochon

      JOURNAL OF SEPARATION SCIENCE26 ( 3-4 ) 155 - 173   3 2003

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    • Fundamental interpretation of the peak profiles in linear reversed-phase liquid chromatography

      K Miyabe, G Guiochon

      ADVANCES IN CHROMATOGRAPHY, VOL 4040   1 - 113   2000

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    • Analysis on mass-transfer phenomena in reversed-phase liquid chromatography

      Miyabe Kanji

      BUNSEKI KAGAKU47 ( 11 ) 769 - 782   11 1998

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      Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)   Publisher：The Japan Society for Analytical Chemistry  

      An analytical study was made concerning mass-transfer phenomena in reversed-phase liquid chromatography (RP-LC). A moment method was applied for analyzing the properties of chromatographic peaks measured under various conditions related to sample substances as well as stationary and mobile phases. First moment analyses provided some pieces of information concerning the mass-transfer equilibrium in RP-LC. The isosteric heat of adsorption (-Q_<st>) was smaller than the corresponding heat of vaporization. The relatively small value of -Q_<st> could be explained by solvophobic theory. From second moment analyses, it was indicated that the contribution of intraparticle diffusion to the overall mass-transfer resistance in a column was usually important, and that surface diffusion played a significantly dominant role for mass transfer in RP packing materials. The activation energy of the surface diffusion (E_s) was larger than -Q_<st> in RP-LC. The correlation between E_s and Q_<st> could be quantitatively interpreted based on the absolute rate theory by assuming that surface diffusion was an activated process similar to molecular diffusion in the liquid phase. The establishment of both an enthalpy-entropy compensation effect and a linear free-energy relation was confirmed irrespective of the separation conditions in RP-LC. A nondimensional rate equation was derived on the basis of moment analysis theory. The equation consists of several terms representing the contributions of mass-transfer processes, such as molecular diffusion, eddy diffusion, fluid-to-particle mass transfer, and intraparticle pore and surface diffusions, to peak spreading. The influence of some operational parameters on the column efficiency was numerically analyzed while considering the individual contribution of each term. It was demonstrated that fundamental studies of surface diffusion provided some essential pieces of information for elucidating the separation mechanism in RP-LC.

      DOI： 10.2116/bunsekikagaku.47.769

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    • 吸着等温線の簡易測定

      宮部寛志

      Adsorpt. News11   5 - 9   5 1997

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      Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (other)   Publisher：日本吸着学会  

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    • 逆相液体クロマト分離系の吸着平衡と吸着速度

      宮部寛志

      Adsorpt. News8   16 - 20   1 1994

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    • The Current Status and Related Issues of Studies on Separation Mechanism of Reversed-Phase Liquid Chromatography

        45 ( 5 ) 343 - 349   5 1993

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      Other Link： http://hdl.handle.net/2261/49272

    • The Current Status and Related Issues of Studies on Optimization Strategies of Separation Conditions of Reversed-Phase Liquid Chromatography

        45 ( 4 ) 275 - 282   4 1993

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      Other Link： http://hdl.handle.net/2261/49258

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    Books and Other Publications

    • 分析化学用語辞典

      日本分析化学会編（ Role： Joint author）

      オーム社  11 2011 

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      Language：Japanese Book type：Dictionary, encyclopedia

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    • 機器分析化学

      津田孝雄, 廣川健他（ Role： Joint author）

      朝倉書店  12 2004 

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      Language：Japanese Book type：Scholarly book

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    Professional Memberships

    Works

    • 有機塩素化合物の還元無害化処理法実証調査 （平成6年度環境庁委託業務結果報告書） Other

      4 1994
      -
      3 1995

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    Research Projects

    • 分子間相互作用および分子集合体界面における物質透過現象の速度論的解析法の開発

      日本学術振興会  科学研究費助成事業 

      宮部 寛志

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      4 2020 - 3 2023

      Grant number：20K05570

      Grant amount：\4290000 （ Direct Cost: \3300000 、 Indirect Cost：\990000 ）

      分子間相互作用や分子集合体の界面における物質透過の速度定数を解析的に求める方法を開発する。高速液体クロマトグラフィー（HPLC）により測定する溶出ピークの形状的特徴をモーメント理論により解析して目的の速度定数を求める。その際、以下の要件を考慮して解析法を開発する。(1)分子の固定化や化学修飾（蛍光標識化）を必要とせず、分子間の本来の相互作用情報をより正確に解析して会合速度定数（ka）と解離速度定数（kd）を定量的に取得することができる。(2)分子集合体（界面活性剤ミセルやリポソーム等）に何等かの化学反応や物理作用を施すことなく、その本来の存在状態により近い実験条件下において外部バルク相から分子集合体内部への界面透過速度定数（kin）、および分子集合体内部から外部バルク相への界面透過速度定数（kout）を定量的に測定することができる。
      本年度はモーメント解析法の妥当性を実証するため、昨年度開発したHPLCデータ解析用モーメント式を利用して分子間相互作用および界面物質透過現象の解析に関する実証実験を以下のように実施した。(1)包接反応系の分子間相互作用：クラウンエーテルや金属イオンの種類を変化させ、クラウンエーテル－金属イオン間の分子間相互作用に対するクラウンエーテルの内部空孔径と金属イオンサイズの関係等の影響について検討した。(2)界面活性剤ミセル系の界面透過現象：レゾルシノールの同族体や異性体を溶質として使用し、ドデシル硫酸ナトリウム（SDS）ミセル界面における溶質の透過現象を解析した。キャピラリー電気泳動（CE）による実験結果との比較により本法による解析結果の妥当性を確認した。(3)タンパク質－化合物間相互作用：逆相液体クロマトグラフィー（RPLC）系を利用し、牛血清アルブミン（BSA）とメチルオレンジの組み合わせをモデル実験系として両者間の相互作用を解析した。

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    • キャピラリー電気泳動を利用する分子間相互作用の速度解析法の開発

      立教大学  立教大学学術推進特別重点資金（立教SFR） 

      宮部寛志

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      4 2015 - 3 2016

      Authorship：Principal investigator  Grant type：Competitive

      外圧印加により会合体をCE分離系内で停止させるChromatographic CE（CCE）法を考案した。CCE概念の導入とモーメント理論の適用により、分子の固定化や化学修飾（蛍光標識化）を必要としない分子間相互作用の会合・解離速度定数の測定法を開発した。本法が分子集合体（界面活性剤ミセル）の界面における物質透過の速度解析にも適用できることを実証した。

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    • クロマトグラフィーによる分子間相互作用の速度解析

      日本学術振興会  科学研究費助成事業 

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      4 2012 - 3 2014

      Grant type：Competitive

      流通式実験法（パルス応答法とピークパーキング法）及びモーメント解析理論を組み合わせ、分子間相互作用の平衡論的情報（親和定数や解離定数）だけではなく、速度論的情報（結合速度定数や解離速度定数）も求めることができる解析法を開発する。
      光学異性体分離系を具体的実験系として取り上げ、本法を適用して速度解析を行う。クロマトグラフィーが物質分離や分子間相互作用の平衡論的解析だけではなく、その速度論的研究へも適用できることを実証する。

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    • モーメント理論に基づくクロマトグラフィー挙動解析基盤技術の確立

      日本学術振興会  科学研究費助成事業 

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      4 2009 - 3 2012

      Grant type：Competitive

      コアシェル粒子分離剤に対応する新規モーメント式を開発し、モーメント解析理論体系の基本的な枠組みを構築した。また、ピークパーキング法に基づく液相系分子拡散係数、液境膜物質移動係数、細孔拡散係数や表面拡散係数等の速度パラメータ測定法を開発した。相互補完的なパルス応答法とピークパーキング法を組み合わせ、様々な実験系に対応できる速度解析実験法を開発した。一方各速度パラメータの推算については、溶媒物性（会合係数）や分離剤の構造特性（円柱状材料の有効長）を考慮してWilke-Chang式やWilson-Geankoplis式を補正する速度物性推算法を開発した。さらに解析手順としては、充填層構造のカラム半径方向不均一性の影響による非対称性ピークの発現機構を解明し、非対称ピーク形状の正確な数値解析法等を開発した。

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    • タンパク質等の拡散係数を簡便かつ正確に測定する技術開発

      その他省庁等  JSTシーズ発掘試験研究 

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      4 2007 - 3 2008

      Grant type：Competitive

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    • 熱力学的特性の解析による逆相液体クロマトグラフィー系の分離挙動解析理論の開発

      日本学術振興会  科学研究費助成事業 

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      4 2005 - 3 2008

      Grant type：Competitive

      逆相液体クロマトグラフィー系の吸着平衡定数と表面拡散係数の温度依存性を解析し、熱力学データを集積した。アルキルリガンドを表面修飾したソフト界面を用いる異相分離系における吸着特性や物質移動挙動を熱力学及びExtrathermodynamicsの観点から研究した。Krugらの解析法を利用して、吸着平衡と表面拡散のエンタルピー－エントロピー補償作用の成立を証明した。その結果に基づき、吸着平衡と表面拡散各々の過程及び、両者間における直線自由エネルギー関係の特徴（温度依存性等）を定量的に解釈するための新たな熱力学的モデルを開発した。また、カラム内や多孔質粒子内における拡散現象の新規解析法としてピークパーキング法を開発した。さらに、様々な構造的特徴（形状や多孔性）を有する各種分離剤に対する新規モーメント解析式を開発し、モーメント解析理論の体系化を図った。

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    • 将来の精密分離のための完全二次元HPLCの開発

      日本学術振興会  科学研究費助成事業 

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      4 2002 - 3 2005

      Grant type：Competitive

      モノリス型シリカC18カラムを二次元目カラムとして用いる単純・完全二次元高速液体クロマトグラフィー(2D-HPLC)システムを開発した。分離性能を高めて2D-HPLCの応用を図ると共に、二次元HPLCの分離挙動や基本性能に関する基礎的研究を行った。

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    • 逆相液体クロマトグラフィー系における物質移動現象の速度論的解析

      日本学術振興会  科学研究費助成事業 

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      4 2000 - 3 2004

      Grant type：Competitive

      逆相液体クロマトグラフィー（RPLC）系の物質移動現象を解析した。固定相として鎖長や修飾率を変えたアルキル基飾シリカゲル、フェニル基修飾シリカゲル、及び多孔性有機ポリマー粒子等）、移動相として主にメタノール/水混合溶液、試料物質としてベンゼン誘導体やフェノール誘導体等を使用するRPLC系においてパルス応答実験を行った。溶出ピーク形状をモーメント解析し、保持平衡及び物質移動速度に関する情報を得た。特に、表面拡散に関する系統的な研究結果に基づき表面拡散現象に対して表面－制限分子拡散モデルを提案し、絶対反応速度論を適用してその定式化を行った。本モデルにより表面拡散の特徴や物質移動機構を統一的に解析すると共に、表面拡散係数の推算法を提案した。またカラム温度条件を変化させてパルス応答実験を行い、保持平衡及び表面拡散の熱力学的特性を解析した。

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    • 逆相液体クロマトグラフィー系の分離挙動に関する研究

      共同研究 

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      4 2000 - 3 2001

      Grant type：Competitive

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    • 動物細胞を用いた農薬類の毒性評価法の開発

      日本学術振興会  科学研究費助成事業 

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      4 1994 - 3 1997

      Grant type：Competitive

      農薬類を水源汚染のモデル物質と見なし、次のような動物細胞の応答に基づく毒性評価手法を開発した。
      (1)動物細胞の機能変化を指標とする毒性評価法
      (2)動物細胞の形態変化を指標とする毒性評価法
      (3)迅速・簡便な毒性評価法
      (4)水処理評価指標としての細胞毒性の検討
      本研究で開発した毒性評価手法を、従来の水質評価法及び既存の変異原性試験と比較した。その結果、将来の飲料水の水質評価指標のひとつに細胞毒性を導入すべきではないかという結論に達した。

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    Industrial property rights

    • Verfahren zum Zersetzen von organischen halogenierten fluchtigen Verbindungen in Wasser

      Miyabe, K, Orita, N, Iwasaki, M, Tsurumaru, Y, Nakahara, T

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      Announcement no：DE69328732(T2)  Date announced：5 10 2000

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    • Verfahren zur Behandlung einer Flussigkeit, die fluchtige, halogenierte organische Verbindungen enthalt

      Miyabe, K, Orita, N, Iwasaki, M, Tsurumaru, Y, Nakahara, T

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      Announcement no：DE69323226(T2)  Date announced：17 6 1999

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    • Method of decomposing volatile organic halogenated compounds in water

      Miyabe, K, Orita, N, Iwasaki, M, Tsurumaru, Y, Nakahara, T

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      Announcement no：EP0745561(A1)  Date announced：4 12 1996

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    • Method of Treatment of a Fluid Containing Volatile Organic Halogenated Compounds

      Miyabe, K, Orita, N, Iwasaki, M, Tsurumaru, Y, Nakahara, T

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      Announcement no：US5531901  Date announced：2 7 1996

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    • Method of Treatment of a Fluid Containing Volatile Organic Halogenated Compounds

      Miyabe, K, Orita, N, Iwasaki, M, Tsurumaru, Y, Nakahara, T

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      Announcement no：US5490941  Date announced：13 2 1996

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    • 嫌気性処理装置からの排出ガスの処理方法

      依田元之, 宮部寛志

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      Announcement no：1995-328387  Date announced：19 12 1995

      Patent/Registration no：3482688  Date issued：17 10 2003

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    • 揮発性有機塩素化合物の分解方法

      山田登, 宮部寛志, 鶴丸陽佳

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      Announcement no：1995-308543  Date announced：28 11 1995

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    • 揮発性有機ハロゲン化合物の気相分解方法

      宮部寛志, 山田登, 鶴丸陽佳

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      Announcement no：1995-303818  Date announced：21 11 1995

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    • 塩化水素含有ガスの中和処理装置

      山田登, 宮部寛志

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      Announcement no：1995-299327  Date announced：14 11 1995

      Patent/Registration no：3480039  Date issued：10 10 2003

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    • 被還元性物質の還元分解装置

      山田登, 宮部寛志, 鶴丸陽佳

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      Announcement no：1995-251029  Date announced：3 10 1995

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    • 揮発性有機ハロゲン化合物の処理方法

      山田登, 宮部寛志, 鶴丸陽佳

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      Announcement no：1995-204625  Date announced：8 8 1995

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    • 揮発性有機ハロゲン化合物含有ガスの処理方法

      宮部寛志, 山田登, 鶴丸陽佳

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      Announcement no：1995-124443  Date announced：16 5 1995

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    • 揮発性有機ハロゲン化合物の処理方法

      山田登, 鶴丸陽佳, 宮部寛志

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      Announcement no：1995-080247  Date announced：28 3 1995

      Patent/Registration no：3326910  Date issued：12 7 2002

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    • 揮発性有機ハロゲン化合物の処理方法

      宮部寛志, 岩崎誠, 鶴丸陽佳

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      Announcement no：1994-343983  Date announced：20 12 1994

      Patent/Registration no：3360353  Date issued：18 10 2002

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    • 揮発性有機ハロゲン化合物の処理方法

      宮部寛志, 鶴丸陽佳, 鍵和田正子, 岩崎誠

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      Announcement no：1994-285334  Date announced：11 10 1994

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    • 揮発性有機ハロゲン化合物の処理方法

      宮部寛志

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      Announcement no：1994-269784  Date announced：27 9 1994

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    • 揮発性有機ハロゲン化合物の処理方法

      宮部寛志, 岩崎誠, 中原敏次, 鶴丸陽佳

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      Announcement no：1994-226046  Date announced：16 8 1994

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    • 揮発性有機ハロゲン化合物の処理方法

      宮部寛志, 鶴丸陽佳, 岩崎誠

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      Announcement no：1994-226048  Date announced：16 8 1994

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    • 揮発性有機ハロゲン化合物含有水の処理方法

      宮部寛志, 鶴丸陽佳, 岩崎誠

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      Announcement no：1994-182361  Date announced：5 7 1994

      Patent/Registration no：3239502  Date issued：12 10 2001

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    • 揮発性有機ハロゲン化合物含有ガスの処理方法

      宮部寛志, 中原敏次, 岩崎誠

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      Announcement no：1994-142454  Date announced：24 5 1994

      Patent/Registration no：3293207  Date issued：5 4 2002

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    • 揮発性有機ハロゲン化合物の還元処理用触媒

      宮部寛志, 中原敏次, 鶴丸陽佳, 岩崎誠

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      Announcement no：1994-134315  Date announced：17 5 1994

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    • 揮発性有機ハロゲン化合物の処理方法

      宮部寛志, 岩崎誠, 中原敏次, 鶴丸陽佳

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      Announcement no：1994-106171  Date announced：19 4 1994

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    • 揮発性有機ハロゲン化合物の処理方法

      中原敏次, 鶴丸陽佳, 宮部寛志, 岩崎誠

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      Announcement no：1994-106172  Date announced：19 4 1994

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    • フロンの分解方法

      中原敏次, 宮部寛志

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      Announcement no：1994-091136  Date announced：5 4 1994

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    • 揮発性有機ハロゲン化合物の処理方法

      宮部寛志, 岩崎誠, 中原敏次, 鶴丸陽佳

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      Announcement no：1994-086990  Date announced：29 3 1994

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    • 揮発性有機ハロゲン化合物含有流体の処理方法

      宮部寛志, 岩崎誠, 中原敏次, 鶴丸陽佳

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      Announcement no：1994-055182  Date announced：1 3 1994

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    • 揮発性有機ハロゲン化合物含有ガスの気相分解処理方法

      織田信博, 宮部寛志

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      Announcement no：1994-031135  Date announced：8 2 1994

      Patent/Registration no：3293181  Date issued：5 4 2002

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    • 揮発性有機ハロゲン化合物の処理方法

      織田信博, 宮部寛志

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      Announcement no：1993-329330  Date announced：14 12 1993

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    • 揮発性有機ハロゲン化合物含有ガスの気相還元分解処理方法

      宮部寛志, 織田信博

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      Announcement no：1993-301025  Date announced：16 11 1993

      Patent/Registration no：3324139  Date issued：5 7 2002

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    • 低沸点有機物の処理装置

      織田信博, 宮部寛志

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      Announcement no：1993-269346  Date announced：19 10 1993

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    • 揮発性有機ハロゲン化合物含有水の処理方法

      宮部寛志, 織田信博

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      Announcement no：1993-269476  Date announced：19 10 1993

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    • A Method of Treatment of a Fluid Containing Volatile Organic Halogenated Compounds

      Miyabe, K, Orita, N, Iwasaki, M, Tsurumaru, Y, Nakahara, T

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      Announcement no：EP0563669(A1)  Date announced：6 10 1993

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    • A Method of Treatment of a Fluid Containing Volatile Organic Halogenated Compounds

      Miyabe, K, Orita, N, Iwasaki, M, Tsurumaru, Y, Nakahara, T

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      Announcement no：AU-A-35247/93  Date announced：30 9 1993

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    • 吸着剤の吸着能の測定方法

      宮部寛志, 鈴木基之

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      Announcement no：1993-034325  Date announced：9 2 1993

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    • イオンクロマトグラフィー方法

      中村幸二, 宮部寛志, 坂本秀一, 古谷英司, 中津川信一

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      Announcement no：1989-320460  Date announced：26 12 1989

      Patent/Registration no：1994271  Date issued：22 11 1995

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    Social Contribution

    • Editor （Chromatography Research International）（Hindawi）

      6 2010 - Present

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    • Editorial Advisory Board （Journal of Separation Science）（Wiley-VCH）

      1 2002 - Present

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    • 富山大学地域連携推進機構産学連携部門「スーパーエンジニア養成コース」講師

      4 2011 - 3 2012

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    • 文部科学省委託事業「社会人の学び直しニーズ対応教育推進プログラム」

      9 2008 - 3 2011

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      “働きながら学ぶ先導的技術者育成事業”（プロフェッショナルエンジニアコース、先端環境・バイオ工学特論Ⅱ）講師

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    • Nature Reader Advisory Panel

      10 2008 - 8 2010

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    • 社団法人富山県計量協会環境計量証明部会クロスチェック研究会講師

      11 2004

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    • 愛知県化学物質適正管理指針検討委員会委員

      4 2003 - 3 2004

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    • 金沢大学薬学部（社会人博士課程）博士論文審査副査

      8 2003

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    • 第3回高校生国際環境サミット富山大会分科会講師

      8 2001

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    • 富山大学リカレント学習コース講師

      11 1999

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