Researcher Profile - SASAKI Naoki

写真b

SASAKI Naoki

*Items subject to periodic update by Rikkyo University (The rest are reprinted from information registered on researchmap.)

Affiliation*

College of Science Department of Chemistry
Graduate School of Science Doctoral Program in Chemistry
Graduate School of Science Master's Program in Chemistry

Title*

Professor

Degree

Ph.D （ 3 2007 The University of Tokyo ）

Homepage

https://www2.rikkyo.ac.jp/web/n_sasaki/

Research Interests

Physical chemistry

Analytical chemistry

Courses in charge*

Academic Year 2025

Campus Career*

4 2023 - Present

College of Science Department of Chemistry Professor
4 2023 - Present

Graduate School of Science Master's Program in Chemistry Professor
4 2023 - Present

Graduate School of Science Doctoral Program in Chemistry Professor
4 2020 - 3 2023

College of Science Department of Chemistry Associate Professor
4 2020 - 3 2023

Graduate School of Science Master's Program in Chemistry Associate Professor
4 2020 - 3 2023

Graduate School of Science Doctoral Program in Chemistry Associate Professor

▼display all

External Link

Profile

Naoki SASAKI received B. Eng. (2002), M. Eng. (2004) and PhD in Engineering (2007) degrees (Applied Chemistry) from the University of Tokyo. After working as a Special Postdoctoral Researcher at RIKEN in 2007 – 2010 and as an Assistant Professor at Japan Women’s University in 2010 – 2013, he served as an Associate Professor (PI) at Toyo University. In 2020, he moved to Rikkyo University as an Associate Professor (PI), and he promoted to Full Professor (PI) in 2023. His current research interests include microfluidic systems for bioanalysis and artificial life.

Research Areas

Nanotechnology/Materials / Basic physical chemistry
Nanotechnology/Materials / Analytical chemistry
Life Science / Biomaterials
Life Science / Biomedical engineering
Nanotechnology/Materials / Nano/micro-systems

Research History

4 2025 - Present

Rikkyo University

▶ More details

researchmap
4 2025 - Present

Rikkyo University

▶ More details

researchmap
4 2024 - Present

Rikkyo University Center for Development and Support of Higher Education Director

▶ More details

researchmap
4 2024 - Present

Saitama University Graduate School of Science and Engineering Adjunct professor

▶ More details

researchmap
4 2023 - Present

Rikkyo University College of Science Department of Chemistry Professor

▶ More details

researchmap
9 2022 - Present

Japan Women's University Faculty of Science Part-time lecturer

▶ More details

researchmap
4 2022 - 3 2024

Rikkyo University Center for Development and Support of Higher Education Vice director

▶ More details

researchmap
4 2020 - 3 2023

Rikkyo University Department of Chemistry, College of Science Associate professor

▶ More details

researchmap
6 2021 - 9 2021

Ochanomizu University Faculty of Science Part-time lecturer

▶ More details

researchmap
4 2016 - 3 2020

Toyo University Department of Applied Chemistry, Faculty of Science and Engineering Associate professor

▶ More details

researchmap
4 2013 - 3 2016

Toyo University Department of Applied Chemistry, Faculty of Science and Engineering Associate professor

▶ More details

researchmap
4 2010 - 3 2013

Japan Women's University Faculty of Science Assistant professor

▶ More details

researchmap
4 2007 - 3 2010

RIKEN Special postdoctoral researcher

▶ More details

researchmap

▼display all

Education

4 2004 - 3 2007

The University of Tokyo Department of Applied Chemistry, School of Engineering Doctor course

▶ More details

Country： Japan

researchmap
4 2002 - 3 2004

The University of Tokyo Department of Applied Chemistry, Graduate School of Engineering Master course

▶ More details

Country： Japan

researchmap
4 1998 - 3 2002

The University of Tokyo Faculty of Engineering Department of Applied Chemistry

▶ More details

Country： Japan

researchmap

Committee Memberships

5 2022 - Present

文部科学省科学技術・学術政策研究所専門調査員

▶ More details

Committee type：Government

researchmap
2020 - 2023

MicroTAS Technical Program Committee

▶ More details

researchmap
4 2019 - 3 2022

化学とマイクロ・ナノシステム学会会誌「化学とマイクロ・ナノシステム」編集委員

▶ More details

Committee type：Academic society

researchmap
4 2018 - 3 2022

日本分析化学会代議員

▶ More details

Committee type：Academic society

researchmap
4 2016 - 3 2020

日本分析化学会「分析化学」編集委員

▶ More details

Committee type：Academic society

researchmap
8 2019 - 8 2019

第32回バイオメディカル分析科学シンポジウム若手シンポジウムオーガナイザー

▶ More details

Committee type：Academic society

researchmap
4 2015 - 3 2018

日本分析化学会関東支部幹事

▶ More details

Committee type：Academic society

researchmap
5 2016 - 5 2016

日本分析化学会第76回分析化学討論会討論主題オーガナイザ『分析化学を支える「マイクロ・ナノ」～「マイクロ・ナノ」を基盤技術とした分析化学の新潮流と将来展望』

▶ More details

Committee type：Academic society

researchmap

▼display all

Awards

12 2024

令和6年度分析イノベーション交流会優秀ポスター賞 M2型マクロファージを組み込んだマイクロ腫瘍モデルにおけるスフェロイドのナノ粒子取り込み評価

初田理紗, 目野敬大, 神澤大志, 章逸汀, 岸村顕広, 佐々木直樹

▶ More details

researchmap
5 2024

第84回分析化学討論会若手ポスター賞物質放出能を持つリポソームのマイクロ流体デバイスによる作製と評価

細川真穂, 章逸汀, 佐々木直樹

▶ More details

researchmap
9 2023

RSC Tokyo International Conference 2023 "Digital Discovery" Poster Prize Development of a microfluidic platform to evaluate nanoparticle uptake by tumor cells in the presence of M2 macrophages

Risa Hatsuta, Yiting Zhang, Naoki Sasaki

▶ More details

researchmap
11 2019

日本化学会第9回CSJ化学フェスタ2019 優秀ポスター発表賞二方向観察可能な膜集積マイクロ流体デバイスを用いる角化細胞層の透過性評価

杉本茉莉花、佐々木直樹

▶ More details

researchmap
9 2019

日本分析化学会第68年会学生ポスター賞無細胞マイクロ血管モデルを用いる腫瘍細胞の血管外遊出アッセイ

浅海裕一郎, 佐々木直樹

▶ More details

researchmap
12 2016

Analytical Sciences Hot article award "A Membrane-Integrated Microfluidic Device to Study Permeation of Nanoparticles through Straight Micropores toward Rational Design of Nanomedicines"

Naoki SASAKI, Mariko TATANOU, Tomoko SUZUKI, Yasutaka ANRAKU, Akihiro KISHIMURA, Kazunori KATAOKA, Kae SATO

▶ More details

Award type：Honored in official journal of a scientific society, scientific journal

researchmap
9 2015

The Japan Society for Analytical Chemistry Award for Young Researchers Development of micro bioanalytical devices based on deductive and constitutive approaches

Naoki SASAKI

▶ More details

researchmap
10 2012

第2回CSJ化学フェスタ2012 優秀ポスター発表賞「リンパ管内皮細胞のマイクロデバイス培養と細胞間接着分子の観察」

佐藤美和, 佐々木直樹, 平川聡史, 佐藤香枝

▶ More details

Country：Japan

researchmap
9 2012

RSC Tokyo International Conference 2012 Poster Presentation Award "Microchip-based in situ Padlock/RCA system for single DNA counting in a cell"

Arisa Kuroda, Reina Ishii, Naoki Sasaki, Mats Nilsson, Kae Sato

▶ More details

researchmap
6 2012

Analytical Sciences Hot article award ”Photochemical immobilization of cells onto a glass substrate for in situ DNA analysis”

Naoki SASAKI, Anri ISU, Reina ISHII, Kae SATO

▶ More details

researchmap

▼display all

Papers

Synthesis and characterization of boron-containing biocompatible polymer-coated Gd2O3 nanoparticles for neutron capture therapy-based theranostics Peer-reviewed

Yu Takai, Ki Chul Park, Naokazu Idota, Naoki Sasaki, Takehiko Tsukahara

Colloids and Surfaces A: Physicochemical and Engineering Aspects711 136328 - 136328 4 2025

▶ More details

Language：English Publishing type：Research paper (scientific journal) Publisher：Elsevier BV

DOI： 10.1016/j.colsurfa.2025.136328

researchmap
A two-way membrane-integrated microfluidic device for evaluation of anti-inflammatory drug through immunohistochemical analysis and permeability assay of keratinocyte cell layers Peer-reviewed

Marika Sugimoto, Naoko Takahashi-Ando, Naoki Sasaki

Talanta Open9 100330 8 2024

▶ More details

Authorship：Last author,　Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：Elsevier BV

DOI： 10.1016/j.talo.2024.100330

researchmap
Bead-Based Padlock Rolling Circle Amplification under Molecular Crowding Conditions: The Effects of Crowder Charge and Size Peer-reviewed

Naoki SASAKI, Chikako Kase, Kae SATO

Analytical Sciences37 ( 5 ) 727 - 732 5 2021

▶ More details

Authorship：Lead author,　Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：Japan Society for Analytical Chemistry

DOI： 10.2116/analsci.20scp14

researchmap
Fabrication of a T-Shaped Microfluidic Channel Using a Consumer Laser Cutter and Application to Monodisperse Microdroplet Formation Peer-reviewed

Naoki Sasaki, Eisuke Sugenami

Micromachines12 ( 2 ) 160 - 160 5 2 2021

▶ More details

Authorship：Lead author,　Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：MDPI AG

The use of micrometer-sized droplets for chemical and biochemical analysis has been widely explored. Photolithography is mainly used to fabricate microfluidic devices, which is often employed to form monodisperse microdroplets. Although photolithography enables precise microfabrication, it is not readily available to biochemists because it requires specialized equipment such as clean room and mask aligners, and expensive consumables such as photoresist and silicon wafers. In this study, we fabricated a microfluidic device using a consumer laser cutter and applied it to droplet formation. Monodisperse microdroplets were formed by using an oil phase for droplet digital polymerase chain reaction (PCR) as the continuous phase and phosphate-buffered saline or polyethylene glycol solution as the dispersed phase. The droplet size decreased as the flow rate of the continuous phase increased and approached a constant value. The method developed in this study can be used to realize microdroplet-based biochemical analysis with simple devices or to construct artificial cells.

DOI： 10.3390/mi12020160

researchmap
Photolithography-free Vessel-on-a-chip to Simulate Tumor Cell Extravasation Peer-reviewed

Yuichiro Asaumi, Naoki Sasaki

Sensors and Materials33 ( 1 ) 241 - 241 22 1 2021

▶ More details

Authorship：Last author,　Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：MYU K.K.

DOI： 10.18494/sam.2021.3073

researchmap
Mechanistic investigation of bead-based padlock rolling circle amplification under molecular crowding conditions Peer-reviewed

Naoki Sasaki, Chikako Kase, Masaki Chou, Genki Nakazato, Kae Sato

Analytical Biochemistry593 113596 3 2020

▶ More details

Authorship：Lead author,　Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：Elsevier BV

DOI： 10.1016/j.ab.2020.113596

researchmap
Photoactivatable hydrogel interfaces for resolving the interplay of chemical, mechanical, and geometrical regulation of collective cell migration Peer-reviewed

Shota Yamamoto, Kei Okada, Naoki Sasaki, Alice Chinghsuan Chang, Kazuo Yamaguchi, Jun Nakanishi

Langmuir35 ( 23 ) 7459 - 7468 6 2019

▶ More details

Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1021/acs.langmuir.8b02371

researchmap
Pancreatic stellate cells derived from human pancreatic cancer demonstrate aberrant SPARC-dependent ECM remodeling in 3D engineered fibrotic tissue of clinically relevant thickness. Peer-reviewed International journal

Hiroyoshi Y Tanaka, Kentaro Kitahara, Naoki Sasaki, Natsumi Nakao, Kae Sato, Hirokazu Narita, Hiroshi Shimoda, Michiya Matsusaki, Hiroshi Nishihara, Atsushi Masamune, Mitsunobu R Kano

Biomaterials192 355 - 367 2 2019

▶ More details

Language：English Publishing type：Research paper (scientific journal)

Desmoplasia is a hallmark of pancreatic cancer and consists of fibrotic cells and secreted extracellular matrix (ECM) components. Various in vitro three-dimensional (3D) models of desmoplasia have been reported, but little is known about the relevant thickness of the engineered fibrotic tissue. We thus measured the thickness of fibrotic tissue in human pancreatic cancer, as defined by the distance from the blood vessel wall to tumor cells. We then generated a 3D fibrosis model with a thickness reaching the clinically observed range using pancreatic stellate cells (PSCs), the main cellular constituent of pancreatic cancer desmoplasia. Using this model, we found that Collagen fiber deposition was increased and Fibronectin fibril orientation drastically remodeled by PSCs, but not normal fibroblasts, in a manner dependent on Transforming Growth Factor (TGF)-β/Rho-Associated Kinase (ROCK) signaling and Matrix Metalloproteinase (MMP) activity. Finally, by targeting Secreted Protein, Acidic and Rich in Cysteine (SPARC) by siRNA, we found that SPARC expression in PSCs was necessary for ECM remodeling. Taken together, we developed a 3D fibrosis model of pancreatic cancer with a clinically relevant thickness and observed aberrant SPARC-dependent ECM remodeling in cancer-derived PSCs.

DOI： 10.1016/j.biomaterials.2018.11.023

PubMed

researchmap
Photolithography-free Skin-on-a-chip for Parallel Permeation Assays Peer-reviewed

Naoki Sasaki, Kimiaki Tsuchiya, Hironori Kobayashi

Sensors and Materials31 ( 1 ) 107 - 115 1 2019

▶ More details

Authorship：Lead author,　Corresponding author Language：English Publishing type：Research paper (scientific journal)

DOI： 10.18494/SAM.2019.2125

researchmap
Label-free rapid separation and enrichment of bone marrow-derived mesenchymal stem cells from a heterogeneous cell mixture using a dielectrophoresis device Peer-reviewed

Junya Yoshioka, Yu Ohsugi, Toru Yoshitomi, Tomoyuki Yasukawa, Naoki Sasaki, Keitaro Yoshimoto

Sensors (Switzerland)18 ( 9 ) 3007 8 9 2018

▶ More details

Language：English Publishing type：Research paper (scientific journal)

DOI： 10.3390/s18093007

Scopus

PubMed

researchmap
Fabrication of Microfluidic Cell Culture Devices Using a Consumer Laser Cutter Peer-reviewed

Naoki SASAKI, Tomomi HAYASHI, Nanako INOUE, Masahiro ONISHI

BUNSEKI KAGAKU67 ( 7 ) 379 - 386 7 2018

▶ More details

Authorship：Lead author,　Corresponding author Language：Japanese Publishing type：Research paper (scientific journal)

DOI： 10.2116/bunsekikagaku.67.379

researchmap
Molecular crowding improves bead-based padlock rolling circle amplification Peer-reviewed

Naoki Sasaki, Yoshitaka Gunji, Chikako Kase, Kae Sato

ANALYTICAL BIOCHEMISTRY519 15 - 18 2 2017

▶ More details

Authorship：Lead author,　Corresponding author Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1016/j.ab.2016.12.002

researchmap
A Membrane-integrated Microfluidic Device to Study Permeation of Nanoparticles through Straight Micropores toward Rational Design of Nanomedicines Peer-reviewed

Naoki Sasaki, Mariko Tatanou, Tomoko Suzuki, Yasutaka Anraku, Akihiro Kishimura, Kazunori Kataoka, Kae Sato

ANALYTICAL SCIENCES32 ( 12 ) 1307 - 1314 12 2016

▶ More details

Language：English Publishing type：Research paper (scientific journal)

DOI： 10.2116/analsci.32.1307

researchmap
Analytical applications of microfluidic vascular models Peer-reviewed

Naoki Sasaki, Kae Sato

Bunseki Kagaku65 ( 5 ) 241 - 247 2016

▶ More details

Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Japan Society for Analytical Chemistry

DOI： 10.2116/bunsekikagaku.65.241

Scopus

researchmap
Patterned Co-culture of Live Cells on a Microchip by Photocrosslinking with Benzophenone Peer-reviewed

Kiichi Sato, Sayaka Kikuchi, Eri Yoshida, Reina Ishh, Naoki Sasaki, Kin-ichi Tsunoda, Kae Sato

ANALYTICAL SCIENCES32 ( 1 ) 113 - 116 1 2016

▶ More details

Language：English Publishing type：Research paper (scientific journal)

DOI： 10.2116/analsci.32.113

researchmap
Alternating Current Cloud Point Extraction on a Microfluidic Chip: the Use of Ferrocenyl Surfactants Peer-reviewed

Yuya Usui, Naoki Sasaki

ANALYTICAL SCIENCES32 ( 1 ) 109 - 111 1 2016

▶ More details

Language：English Publishing type：Research paper (scientific journal)

DOI： 10.2116/analsci.32.109

researchmap
Microcirculation-on-a-Chip: A Microfluidic Platform for Assaying Blood- and Lymphatic-Vessel Permeability Peer-reviewed

Miwa Sato, Naoki Sasaki, Manabu Ato, Satoshi Hirakawa, Kiichi Sato, Kae Sato

PLOS ONE10 ( 9 ) e0137301 9 2015

▶ More details

Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1371/journal.pone.0137301

researchmap
Alternating current cloud point extraction on a microchip: The effect of electrode geometry Peer-reviewed

Naoki Sasaki, Chisaki Maekawa, Kae Sato

ELECTROPHORESIS36 ( 3 ) 424 - 427 2 2015

▶ More details

Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1002/elps.201400410

researchmap
AC electrokinetics for bioanalysis on a microchip Peer-reviewed

Naoki Sasaki

Bunseki Kagaku64 ( 1 ) 1 - 8 2015

▶ More details

Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Japan Society for Analytical Chemistry

DOI： 10.2116/bunsekikagaku.64.1

Scopus

researchmap
Magnetic resonance imaging of a microvascular-interstitium model on a microfluidic device Peer-reviewed

Naoki Sasaki, Jun-Ichiro Jo, Ichio Aoki, Kae Sato

ANALYTICAL BIOCHEMISTRY458 72 - 74 8 2014

▶ More details

Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1016/j.ab.2014.03.020

researchmap
Microfluidics for nano-pathophysiology Peer-reviewed

Kae Sato, Naoki Sasaki, Helene Andersson Svahn, Kiichi Sato

ADVANCED DRUG DELIVERY REVIEWS74 115 - 121 7 2014

▶ More details

Language：English

DOI： 10.1016/j.addr.2013.08.009

researchmap
Bead-based padlock rolling circle amplification for single DNA molecule counting Peer-reviewed

Kae Sato, Reina Ishii, Naoki Sasaki, Kiichi Sato, Mats Nilsson

ANALYTICAL BIOCHEMISTRY437 ( 1 ) 43 - 45 6 2013

▶ More details

Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1016/j.ab.2013.02.016

PubMed

researchmap
Development of an ex-vivo lymphatic vascular model Peer-reviewed

Miwa Sato, Naoki Sasaki, Satoshi Hirakawa, Kae Sato, Kiichi Sato

17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 20132 1093 - 1095 2013

▶ More details

Language：English Publishing type：Research paper (international conference proceedings) Publisher：Chemical and Biological Microsystems Society

Scopus

researchmap
Alternating current cloud point extraction on a microchip: A comprehensive study Peer-reviewed

Naoki Sasaki, Azusa Takemura, Kae Sato

ELECTROPHORESIS33 ( 21 ) 3159 - 3165 11 2012

▶ More details

Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1002/elps.201200229

PubMed

researchmap
Fluid mixing using AC electrothermal flow on meandering electrodes in a microchannel Peer-reviewed

Naoki Sasaki, Takehiko Kitamori, Haeng-Boo Kim

ELECTROPHORESIS33 ( 17 ) 2668 - 2673 9 2012

▶ More details

Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1002/elps.201200099

PubMed

researchmap
A palmtop-sized microfluidic cell culture system driven by a miniaturized infusion pump Peer-reviewed

Naoki Sasaki, Mika Shinjo, Satoshi Hirakawa, Masahiro Nishinaka, Yo Tanaka, Kazuma Mawatari, Takehiko Kitamori, Kae Sato

ELECTROPHORESIS33 ( 12 ) 1729 - 1735 7 2012

▶ More details

Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1002/elps.201100691

PubMed

researchmap
Photochemical Immobilization of Cells onto a Glass Substrate for in situ DNA Analysis Peer-reviewed

Naoki Sasaki, Anri Isu, Reina Ishii, Kae Sato

ANALYTICAL SCIENCES28 ( 6 ) 537 - 539 6 2012

▶ More details

Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)

DOI： 10.2116/analsci.28.537

researchmap
Hydrodynamic Cell Pairing and Cell Fusion through a Microslit on a Microfluidic Device Peer-reviewed

Naoki Sasaki, Jiansheng Gong, Makoto Sakuragi, Kazuo Hosokawa, Mizuo Maeda, Yoshihiro Ito

JAPANESE JOURNAL OF APPLIED PHYSICS51 ( 3 ) 030206 3 2012

▶ More details

Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1143/JJAP.51.030206

researchmap
Recent Applications of AC Electrokinetics in Biomolecular Analysis on Microfluidic Devices Peer-reviewed

Naoki Sasaki

ANALYTICAL SCIENCES28 ( 1 ) 3 - 8 1 2012

▶ More details

Authorship：Lead author,　Last author,　Corresponding author Language：English Publishing type：Research paper (scientific journal)

DOI： 10.2116/analsci.28.3

researchmap
Photo-immobilization of cells for in situ DNA analysis Peer-reviewed

Naoki Sasaki, Anri Isu, Reina Ishii, Kae Sato

Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 1252 - 1254 2012

▶ More details

Authorship：Lead author Language：English Publishing type：Research paper (international conference proceedings) Publisher：Chemical and Biological Microsystems Society

Scopus

researchmap
Mechanistic characterization of alternating current cloud point extraction in a microchannel: Extraction under physiological temperature Peer-reviewed

Naoki Sasaki, Azusa Takemura, Kae Sato

Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 896 - 898 2012

▶ More details

Authorship：Lead author Language：English Publishing type：Research paper (international conference proceedings) Publisher：Chemical and Biological Microsystems Society

Scopus

researchmap
Counting single DNA molecule by on-bead rolling circle amplification for quantitative analyses Peer-reviewed

Reina Ishii, Naoki Sasaki, Kiichi Sato, Kazuma Mawatari, Mats Nilsson, Takehiko Kitamori, Kae Sato

15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 20111 70 - 72 2011

▶ More details

Language：English Publishing type：Research paper (international conference proceedings)

Scopus

researchmap
Development of a microfluidic southern hybridization analysis system using microbeads Peer-reviewed

Kae Sato, Mami Nishikawa, Naoki Sasaki, Kiichi Sato

15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 20111 296 - 298 2011

▶ More details

Language：English Publishing type：Research paper (international conference proceedings)

Scopus

researchmap
Experimental and Theoretical Characterization of an AC Electroosmotic Micromixer Peer-reviewed

Naoki Sasaki, Takehiko Kitamori, Haeng-Boo Kim

ANALYTICAL SCIENCES26 ( 7 ) 815 - 819 7 2010

▶ More details

Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)

DOI： 10.2116/analsci.26.815

researchmap
Artificial chaperone-assisted refolding in a microchannel Peer-reviewed

Etsushi Yamamoto, Satoshi Yamaguchi, Naoki Sasaki, Haeng-Boo Kim, Takehiko Kitamori, Teruyuki Nagamune

BIOPROCESS AND BIOSYSTEMS ENGINEERING33 ( 1 ) 171 - 177 1 2010

▶ More details

Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1007/s00449-009-0374-1

researchmap
Alternating current cloud point extraction on a microchip for preconcentration of membrane-associated biomolecules Peer-reviewed

Naoki Sasaki, Kazuo Hosokawa, Mizuo Maeda

LAB ON A CHIP9 ( 9 ) 1168 - 1170 2009

▶ More details

Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1039/b901007f

researchmap
Analysis of fluid motion in alternating current cloud point extraction Peer-reviewed

Naoki Sasaki, Kazuo Hosokawa, Mizuo Maeda

Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences 43 - 45 2009

▶ More details

Authorship：Lead author Language：English Publishing type：Research paper (international conference proceedings) Publisher：Chemical and Biological Microsystems Society

Scopus

researchmap
AC electrokinetic phase separation, focusing and concentration in microchannel Peer-reviewed

Naoki Sasaki, Kazuo Hosokawa, Mizuo Maeda

12th International Conference on Miniaturized Systems for Chemistry and Life Sciences - The Proceedings of MicroTAS 2008 Conference 754 - 756 2008

▶ More details

Authorship：Lead author Language：English Publishing type：Research paper (international conference proceedings) Publisher：Chemical and Biological Microsystems Society

Scopus

researchmap
Rapid mixing by ac electrothermal flow Peer-reviewed

Naoki Sasaki, Takehiko Kitamori, Haeng-Boo Kim

Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 916 - 918 2007

▶ More details

Authorship：Lead author Language：English Publishing type：Research paper (international conference proceedings) Publisher：Chemical and Biological Microsystems Society

Scopus

researchmap
AC electroosmotic micromixer for chemical processing in a microchannel Peer-reviewed

Naoki Sasaki, Takehiko Kitamori, Haeng-Boo Kim

Lab on a Chip6 ( 4 ) 550 - 554 2006

▶ More details

Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1039/b515852d

researchmap
Spectroelectrochemical detection using thermal lens microscopy with a glass-substrate microelectrode-microchannel chip Peer-reviewed

Haeng-Boo Kim, Tomokazu Hagino, Naoki Sasaki, Noriyuki Watanabe, Takehiko Kitamori

Journal of Electroanalytical Chemistry577 ( 1 ) 47 - 53 3 2005

▶ More details

Language：English Publishing type：Research paper (scientific journal) Publisher：Elsevier BV

DOI： 10.1016/j.jelechem.2004.11.012

researchmap

▼display all

Misc.

先んずる者として Invited

佐々木直樹

ぶんせき ( 1 ) 33 1 2024

▶ More details

Language：Japanese

researchmap
Skin-on-a-chipの研究動向 Invited Peer-reviewed

杉本茉莉花, 佐々木直樹

化学とマイクロ・ナノシステム18 ( 2 ) 10 2019

▶ More details

Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)

researchmap
粒ぞろいの細胞もどきを作る Invited Peer-reviewed

佐々木直樹

ぶんせき ( 6 ) 215 - 215 6 2016

▶ More details

Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)

researchmap
光誘起動電現象で生体分子を濃縮する

佐々木直樹

ぶんせき ( 7 ) 361 2010

▶ More details

researchmap

Presentations

M2型マクロファージを組み込んだマイクロ腫瘍モデルの構築とナノ粒子取り込み評価への応用

初田理紗, 目野敬大, 神澤大志, 章逸汀, 岸村顕広, 佐々木直樹

日本化学会第105春季年会 28 3 2025

▶ More details

Event date： 26 3 2025 - 29 3 2025

Language：Japanese Presentation type：Oral presentation (general)

researchmap
親水/疎水コンポジットデバイスを用いたリポソームの形成に関する研究

章逸汀, 佐々木直樹

第8回分子ロボティクス年次大会 13 3 2025

▶ More details

Event date： 12 3 2025 - 13 3 2025

Language：Japanese Presentation type：Oral presentation (general)

researchmap
血管新生実験と薬物評価に向けた並行多孔膜組み込みマイクロ流体デバイスの開発

加藤はる香, 章逸汀, 佐々木直樹

令和6年度分析イノベーション交流会 24 12 2024

▶ More details

Event date： 23 12 2024 - 24 12 2024

Language：Japanese Presentation type：Poster presentation

researchmap
M2型マクロファージを組み込んだマイクロ腫瘍モデルにおけるスフェロイドのナノ粒子取り込み評価

初田理紗, 目野敬大, 神澤大志, 章逸汀, 岸村顕広, 佐々木直樹

令和6年度分析イノベーション交流会 24 12 2024

▶ More details

Event date： 23 12 2024 - 24 12 2024

Language：Japanese Presentation type：Poster presentation

researchmap
親水/疎水コンポジットデバイスによるリポソーム形成条件の検討

章逸汀, 佐々木直樹

化学とマイクロ・ナノシステム学会第50回研究会 26 11 2024

▶ More details

Event date： 25 11 2024 - 28 11 2024

Language：Japanese Presentation type：Poster presentation

researchmap
マイクロ流体デバイスで作製したリポソームからの制御された物質放出

細川真穂, 章逸汀, 佐々木直樹

令和6年度日本分析化学会関東支部若手交流会 23 11 2024

▶ More details

Event date： 22 11 2024 - 23 11 2024

Language：Japanese Presentation type：Poster presentation

researchmap
酵素反応と自然乳化を利用した水性二相マイクロ液滴内での双方向相変換

藤田夏葉, 章逸汀, 佐々木直樹

令和6年度日本分析化学会関東支部若手交流会 23 11 2024

▶ More details

Event date： 22 11 2024 - 23 11 2024

Language：Japanese Presentation type：Poster presentation

researchmap
腫瘍微小環境を構成する様々な細胞種の共培養下における細胞密度と細胞接着性の評価

田口真央, 章逸汀, 佐々木直樹

令和6年度日本分析化学会関東支部若手交流会 23 11 2024

▶ More details

Event date： 22 11 2024 - 23 11 2024

Language：Japanese Presentation type：Poster presentation

researchmap
血管新生アッセイのための並行多孔膜組み込みマイクロ流体デバイスの開発

加藤はる香, 章逸汀, 佐々木直樹

令和6年度日本分析化学会関東支部若手交流会 23 11 2024

▶ More details

Event date： 22 11 2024 - 23 11 2024

Language：Japanese Presentation type：Poster presentation

researchmap
ナノ粒子取り込み評価用マイクロ腫瘍モデルにおけるスフェロイドとM2型マクロファージの共培養法の検討

初田理紗, 章逸汀, 佐々木直樹

令和6年度日本分析化学会関東支部若手交流会 23 11 2024

▶ More details

Event date： 22 11 2024 - 23 11 2024

Language：Japanese Presentation type：Poster presentation

researchmap
水性二相マイクロ液滴内での双方向相変換に基づく細胞内相分離モデルの構築

藤田夏葉, 章逸汀, 佐々木直樹

第14回CSJ化学フェスタ2024 24 10 2024

▶ More details

Event date： 22 10 2024 - 24 10 2024

Language：Japanese Presentation type：Poster presentation

researchmap
M2型マクロファージを組み込んだ多孔膜垂直配置マイクロ腫瘍モデルの開発

初田理紗, 章逸汀, 佐々木直樹

第14回CSJ化学フェスタ2024 24 10 2024

▶ More details

Event date： 22 10 2024 - 24 10 2024

Language：Japanese Presentation type：Poster presentation

researchmap
マイクロ流体デバイスを用いる細胞サイズゼラチン微粒子の作製とアビジン修飾 Invited

高木美紀, 章逸汀, 佐々木直樹

第14回CSJ化学フェスタ2024 24 10 2024

▶ More details

Event date： 22 10 2024 - 24 10 2024

Language：Japanese Presentation type：Poster presentation

researchmap
並行多孔膜組み込みマイクロ流体デバイスを用いた血管新生モデルの開発

加藤はる香, 章逸汀, 佐々木直樹

第14回CSJ化学フェスタ2024 23 10 2024

▶ More details

Event date： 22 10 2024 - 24 10 2024

Language：Japanese Presentation type：Poster presentation

researchmap
腫瘍微小環境を構成する様々な細胞種の共培養下における細胞密度と細胞接着性の評価

田口真央, 章逸汀, 佐々木直樹

第14回CSJ化学フェスタ2024 23 10 2024

▶ More details

Event date： 22 10 2024 - 24 10 2024

Language：Japanese Presentation type：Poster presentation

researchmap
マイクロ流体デバイスで作製したリポソームからの物質放出時間の制御

細川真穂, 章逸汀, 佐々木直樹

第14回CSJ化学フェスタ2024 22 10 2024

▶ More details

Event date： 22 10 2024 - 24 10 2024

Language：Japanese Presentation type：Poster presentation

researchmap
A simple method of forming liposome by using hydrophilic-hydrophobic composite microfluidic devices

Yiting Zhang, Naoki Sasaki

The 28th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2024) 15 10 2024

▶ More details

Event date： 13 10 2024 - 17 10 2024

Language：English Presentation type：Poster presentation

researchmap
親水/疎水コンポジットマイクロ流体デバイスを用いるリポソーム作製

章逸汀, 佐々木直樹

日本分析化学会第73年会 12 9 2024

▶ More details

Event date： 11 9 2024 - 13 9 2024

Language：Japanese Presentation type：Oral presentation (general)

researchmap
Investigation of cell types suitable for the reconstitution of cancer tissue

Mao Taguchi, Yiting Zhang, Naoki Sasaki

RSC-JAIMA Symposium on Analytical Chemistry 2024 5 9 2024

▶ More details

Event date： 5 9 2024 - 6 9 2024

Language：English Presentation type：Poster presentation

researchmap
A microfluidic model to evaluate nanoparticle uptake by tumor cells in the presence of M2 macrophages

Risa Hatsuta, Yiting Zhang, Naoki Sasaki

RSC-JAIMA Symposium on Analytical Chemistry 2024 5 9 2024

▶ More details

Event date： 5 9 2024 - 6 9 2024

Language：English Presentation type：Poster presentation

researchmap
Formation of liposomes and controlled release of their contents on microfluidic devices

Maho Hosokawa, Yiting Zhang, Naoki Sasaki

RSC-JAIMA Symposium on Analytical Chemistry 2024 5 9 2024

▶ More details

Event date： 5 9 2024 - 6 9 2024

Language：English Presentation type：Poster presentation

researchmap
Development of a dual-membrane microfluidic device for angiogenesis assays

Haruka Kato, Yiting Zhang, Naoki Sasaki

RSC-JAIMA Symposium on Analytical Chemistry 2024 5 9 2024

▶ More details

Event date： 5 9 2024 - 6 9 2024

Language：English Presentation type：Poster presentation

researchmap
Bidirectional phase transition in aqueous two-phase microdroplets as a model of liquid-liquid phase separation in living cells

Natsuha Fujita, Yiting Zhang, Naoki Sasaki

RSC-JAIMA Symposium on Analytical Chemistry 2024 5 9 2024

▶ More details

Event date： 5 9 2024 - 6 9 2024

Language：English Presentation type：Poster presentation

researchmap
細胞様液滴は薬剤評価系になりうるか Invited

佐々木直樹

第21回次世代を担う若手のためのフィジカル・ファーマフォーラム（PPF2024） 22 8 2024

▶ More details

Event date： 22 8 2024 - 23 8 2024

Language：Japanese Presentation type：Oral presentation (invited, special)

researchmap
腫瘍組織に関連する様々な細胞種の共培養下における細胞密度と接着性の評価

田口真央, 章逸汀, 佐々木直樹

第84回分析化学討論会 18 5 2024

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
酵素反応と自然乳化を利用した水性二相マイクロ液滴の可逆相分離

藤田夏葉, 章逸汀, 佐々木直樹

第84回分析化学討論会 18 5 2024

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
並行多孔膜組み込みマイクロ流体デバイスを用いた血管新生実験の実証

加藤はる香, 章逸汀, 佐々木直樹

第84回分析化学討論会 18 5 2024

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
物質放出能を持つリポソームのマイクロ流体デバイスによる作製と評価

細川真穂, 章逸汀, 佐々木直樹

第84回分析化学討論会 18 5 2024

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
マイクロ流体デバイスを用いる細胞サイズゼラチン微粒子の作製と表面機能化

高木美紀, 章逸汀, 佐々木直樹

第84回分析化学討論会 18 5 2024

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
細胞共培養可能な多孔膜垂直配置マイクロ腫瘍モデルにおけるナノ粒子の取り込み評価

初田理紗, 章逸汀, 佐々木直樹

第84回分析化学討論会 18 5 2024

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
Microfluidicsを基盤とする構成的生命分析化学 Invited

佐々木直樹

第６回生体膜デザインコンファレンス 31 1 2024

▶ More details

Language：Japanese Presentation type：Oral presentation (invited, special)

researchmap
マイクロ液滴内相分離の酵素反応による制御

藤田夏葉, 章逸汀, 佐々木直樹

第13回CSJ化学フェスタ2023 19 10 2023

▶ More details

Event date： 17 10 2023 - 19 10 2023

Language：Japanese Presentation type：Poster presentation

researchmap
多孔膜垂直配置マイクロ腫瘍モデルにおける細胞共培養法の検討

初田理紗, 章逸汀, 佐々木直樹

第13回CSJ化学フェスタ2023 19 10 2023

▶ More details

Event date： 17 10 2023 - 19 10 2023

Language：Japanese Presentation type：Poster presentation

researchmap
血管新生実験に応用可能な並行多孔膜組み込みマイクロデバイスの開発

加藤はる香, 章逸汀, 佐々木直樹

第13回CSJ化学フェスタ2023 19 10 2023

▶ More details

Event date： 17 10 2023 - 19 10 2023

Language：Japanese Presentation type：Poster presentation

researchmap
Spontaneous dynamic microcompartmentation in cell-sized microdroplets

Naoki Sasaki, Sakurako Kojima

The 27th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2023) 16 10 2023

▶ More details

Event date： 15 10 2023 - 19 10 2023

Language：English Presentation type：Poster presentation

researchmap
Development of a microfluidic platform to evaluate nanoparticle uptake by tumor cells in the presence of M2 macrophages

Risa Hatsuta, Yiting Zhang, Naoki Sasaki

RSC Tokyo International Conference 2023 8 9 2023

▶ More details

Event date： 7 9 2023 - 8 9 2023

Language：English Presentation type：Poster presentation

researchmap
Angiogenesis model on a microfluidic device with vertically aligned porous membranes

Yiting Zhang, Haruka Kato, Naoki Sasaki

RSC Tokyo International Conference 2023 8 9 2023

▶ More details

Event date： 7 9 2023 - 8 9 2023

Language：English Presentation type：Poster presentation

researchmap
Microfluidic fabrication of cell-sized gelatin microparticles

Miki Takagi, Yiting Zhang, Naoki Sasaki

RSC Tokyo International Conference 2023 8 9 2023

▶ More details

Event date： 7 9 2023 - 8 9 2023

Language：English Presentation type：Poster presentation

researchmap
細胞様液滴における分子・粒子の局在化と液滴のアレイ化

小嶋櫻子, 坂上欧介, 佐々木直樹

第83回分析化学討論会 21 5 2023

▶ More details

Event date： 20 5 2023 - 21 5 2023

Language：Japanese Presentation type：Oral presentation (general)

researchmap
多孔膜垂直配置マイクロ流体デバイスによる血管新生モデルの構築

加藤はる香, 佐々木直樹

化学とマイクロ・ナノシステム学会第47回研究会 14 5 2023

▶ More details

Event date： 13 5 2023 - 14 5 2023

Language：Japanese Presentation type：Poster presentation

researchmap
民生用レーザー加工機によるマイクロ液滴形成・アレイ化デバイスの作製

坂上欧介, 小嶋櫻子, 佐々木直樹

化学とマイクロ・ナノシステム学会第47回研究会 14 5 2023

▶ More details

Event date： 13 5 2023 - 14 5 2023

Language：Japanese Presentation type：Poster presentation

researchmap
Organ-on-a-Chip with vertically arranged porous membranes Invited

Naoki Sasaki

Pittcon 2023 21 3 2023

▶ More details

Language：English Presentation type：Oral presentation (invited, special)

researchmap
自然乳化と水性二相系を利用するマイクロ液滴内相分離

小嶋櫻子, 佐々木直樹

化学とマイクロ・ナノシステム学会第46回研究会 15 11 2022

▶ More details

Event date： 14 11 2022 - 16 11 2022

Language：Japanese Presentation type：Poster presentation

researchmap
自然乳化を利用したマイクロ液滴内相分離

小嶋櫻子, 佐々木直樹

第12回CSJ化学フェスタ2022 19 10 2022

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
細胞共培養のための多孔膜垂直配置マイクロ流体デバイスの開発

初田理紗, 佐々木直樹

第12回CSJ化学フェスタ2022 19 10 2022

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
温度相転移を利用するマイクロ液滴・微粒子形成システムの構築

高木美紀, 佐々木直樹

第12回CSJ化学フェスタ2022 19 10 2022

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
マイクロ流体デバイスを用いる細胞様液滴の形成

二宮駿斗, 黒須梨沙, 杉井菜々花, 佐々木直樹

日本分析化学会第71年会 16 9 2022

▶ More details

Language：Japanese Presentation type：Oral presentation (general)

researchmap
22世紀の機器分析 Invited

佐々木直樹

第34回環境工学連合講演会 31 5 2022

▶ More details

Language：Japanese Presentation type：Oral presentation (invited, special)

researchmap
Padlock/RCA法と金ナノ粒子を利用する目視核酸検出

佐々木直樹, 寺澤菜都

第82回分析化学討論会 14 5 2022

▶ More details

Language：Japanese Presentation type：Oral presentation (general)

researchmap
マイクロ液滴形成デバイス

佐々木直樹

令和3年度分析イノベーション交流会 26 1 2022

▶ More details

Language：Japanese Presentation type：Oral presentation (general)

researchmap
二方向観察可能なskin-on-a-chipによる抗炎症剤評価（3）：免疫細胞の遊走評価への応用

杉本茉莉花, 安藤直子, 佐々木直樹

第81回分析化学討論会 23 5 2021

▶ More details

Language：Japanese Presentation type：Oral presentation (general)

researchmap
多孔膜垂直配置マイクロ流体デバイス

佐々木直樹

令和2年度分析イノベーション交流会 26 2 2021

▶ More details

Event date： 25 2 2021 - 26 2 2021

Language：Japanese Presentation type：Oral presentation (general)

researchmap
Simulation of tumor cell extravasation on a photolithography-free microfluidic device

Yuichiro Asaumi, Naoki Sasaki

The 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2020) 6 10 2020

▶ More details

Event date： 5 10 2020 - 9 10 2020

Language：English Presentation type：Poster presentation

researchmap
二方向観察可能なskin-on-a-chipによる抗炎症剤評価（2）：トリコテセン類への応用

杉本茉莉花、安藤直子、佐々木直樹

日本化学会第100春季年会 23 3 2020

▶ More details

Event date： 22 3 2020 - 25 3 2020

Language：Japanese Presentation type：Oral presentation (general)

researchmap
二方向観察可能なskin-on-a-chip による抗炎症剤評価

杉本茉莉花、佐々木直樹

化学とマイクロ・ナノシステム学会第40回研究会 19 11 2019

▶ More details

Event date： 19 11 2019 - 21 11 2019

Language：Japanese Presentation type：Poster presentation

researchmap
腫瘍細胞の血管外遊出を評価するマイクロデバイスの開発

浅海裕一郎、佐々木直樹

化学とマイクロ・ナノシステム学会第40回研究会 19 11 2019

▶ More details

Event date： 19 11 2019 - 21 11 2019

Language：Japanese Presentation type：Poster presentation

researchmap
A TWO-WAY MEMBRANE-INTEGRATED MICROFLUIDIC DEVICE FOR PERMEATION ASSAYS International conference

Marika Sugimoto, Keisuke Yanagisawa, Naoki Sasaki

The 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2019) 27 10 2019

▶ More details

Language：English Presentation type：Poster presentation

researchmap
EXTRAVASATION OF SOFT NANOPARTICLES SIMULATED ON AN EASY-TO-OBSERVE MEMBRANE-INTEGRATED MICROFLUIDIC DEVICE International conference

Mayu Watanabe, Yumi Moriya, Hiroaki Matsuba, Akihiro Kishimura, Yoshiki Katayama, Naoki Sasaki

The 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2019) 27 10 2019

▶ More details

Language：English Presentation type：Poster presentation

researchmap
二方向観察可能な膜集積マイクロ流体デバイスを用いる角化細胞層の透過性評価

杉本茉莉花, 佐々木直樹

第9回CSJ化学フェスタ2019 15 10 2019

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
Tumor cell extravasation assay on a photolithography-free microfluidic device International conference

Yuichiro Asaumi, Naoki Sasaki

Lab-on-a-Chip & Microfluidics World Congress 2019 7 10 2019

▶ More details

Language：English Presentation type：Poster presentation

researchmap
無細胞マイクロ血管モデルを用いる腫瘍細胞の血管外遊出アッセイ

浅海裕一郎, 佐々木直樹

日本分析化学会第68年会 11 9 2019

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
二方向観察可能なマイクロ流体デバイスを用いる細胞層の透過性評価

杉本茉莉花, 佐々木直樹

日本分析化学会第68年会 11 9 2019

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
A cell-free vascular model for tumour cell extravasation assay International conference

Yuichiro Asaumi, Naoki Sasaki

RSC Tokyo International Conference 2019 4 9 2019

▶ More details

Language：English Presentation type：Poster presentation

researchmap
Evaluation of permeability of keratinocyte layers using a two-way membrane-integrated microfluidic device International conference

Marika Sugimoto, Keisuke Yanagisawa, Naoki Sasaki

RSC Tokyo International Conference 2019 4 9 2019

▶ More details

Language：English Presentation type：Poster presentation

researchmap
Organ-on-a-chipによる臓器機能再現 Invited

佐々木直樹

第32回バイオメディカル分析科学シンポジウム 24 8 2019

▶ More details

Language：Japanese Presentation type：Oral presentation (invited, special)

researchmap
Organ-on-a-chip による疑似臓器構築 Invited

佐々木直樹

第32回日本Archaea研究会講演会 20 7 2019

▶ More details

Language：Japanese Presentation type：Oral presentation (invited, special)

researchmap
Photolithography-free microfluidic device to study tumor cell extravasation

Yuichiro Asaumi, Naoki Sasaki

The 99th CSJ Annual Meeting 16 3 2019

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
A dual-membrane microfluidic device for chemotaxis assays of immune cells International conference

Marika Sugimoto, Naoki Sasaki

3rd International Symposium on Nanoarchitectonics for Mechanobiology 7 3 2019

▶ More details

Language：English Presentation type：Poster presentation

researchmap
Photolithography-free microfluidic device to evaluate tumor cell migration International conference

Yuichiro Asaumi, Naoki Sasaki

3rd International Symposium on Nanoarchitectonics for Mechanobiology 7 3 2019

▶ More details

Language：English Presentation type：Poster presentation

researchmap
無細胞マイクロ腫瘍血管モデルを用いるナノ粒子の血管漏出性シミュレーション

守谷侑美, 佐々木直樹

第28回日本MRS年次大会 18 12 2018

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
A DUAL-MEMBRANE MICROFLUIDIC DEVICE FOR CELL MIGRATION ASSAY International conference

Marika SUGIMOTO, Fuka NAGATOMI, Naoki SASAKI

The 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2018) 11 11 2018

▶ More details

Language：English Presentation type：Poster presentation

researchmap
PHOTOLITHOGRAPHY-FREE TUMOR-ON-A-CHIP TO STUDY NANOPARTICLE EXTRAVASATION International conference

Yuki Ichikawa, Tomomi Hayashi, Naoki Sasaki

The 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2018) 11 11 2018

▶ More details

Language：English Presentation type：Poster presentation

researchmap
A MEMBRANE-INTEGRATED MICROFLUIDIC DEVICE FOR SIMULATING NANOPARTICLE EXTRAVASATION IN TUMOR MICROENVIRONMENT International conference

Yumi Moriya, Naoki Sasaki

The 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2018) 11 11 2018

▶ More details

Language：English Presentation type：Poster presentation

researchmap
無細胞マイクロ血管モデルを用いるナノ粒子の透過性評価

守谷侑美, 紺野仁美, 佐々木直樹

日本分析化学会第67年会 12 9 2018

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
並行多孔膜組み込みマイクロデバイスによる細胞遊走アッセイ

杉本茉莉花, 永富風花, 佐々木直樹

日本分析化学会第67年会 12 9 2018

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
多孔膜垂直配置マイクロ流体デバイスを用いるバイオ分析 Invited

佐々木直樹

バイオメディカルエンジニアリング新技術説明会 11 9 2018

▶ More details

Language：Japanese Presentation type：Oral presentation (invited, special)

researchmap
疑似細胞空間・疑似組織を基盤とするバイオ分析 Invited

佐々木直樹

首都圏産業活性化協会第31回医療イノベーションフォーラム 1 6 2018

▶ More details

Language：Japanese Presentation type：Oral presentation (invited, special)

researchmap
誰でも作れるマイクロ流体デバイス Invited

佐々木直樹

彩の国ビジネスアリーナ2018 技術シーズ発表会 24 1 2018

▶ More details

Language：Japanese Presentation type：Oral presentation (invited, special)

researchmap
ナノ薬剤開発のための無細胞マイクロ血管モデル Invited

佐々木直樹

第27回日本MRS年次大会 5 12 2017

▶ More details

Language：Japanese Presentation type：Oral presentation (invited, special)

researchmap
Simulation of nanoparticle extravasation using an easy-to-observe membrane-intgrated microfluidic device International conference

Yumi MORIYA, Miki ODANAKA, Naoki SASAKI

The 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017) 22 10 2017

▶ More details

Language：English Presentation type：Poster presentation

researchmap
マイクロビーズPadlock/RCA法における高分子の影響

加瀬央子, 佐々木直樹, 佐藤香枝

第7回CSJ化学フェスタ2017 17 10 2017

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
マイクロ流体デバイスと疑似血液を用いるナノ粒子の血管透過性評価

守谷侑美, 小田中美希, 佐々木直樹

第7回CSJ化学フェスタ2017 17 10 2017

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
無細胞血管－間質マイクロモデルを用いるナノ粒子の透過性評価

守谷侑美, 小田中美希, 佐々木直樹

化学とマイクロ・ナノシステム学会第36回研究会 4 10 2017

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
鋸型電極デバイスの誘電泳動を利用するヒト骨髄由来細胞の非標識な分離と濃縮

吉岡純矢, 大杉悠, 吉冨徹, 安川智之, 佐々木直樹, 吉本敬太郎

日本分析化学会第66年会 9 9 2017

▶ More details

Language：Japanese Presentation type：Oral presentation (general)

researchmap
マイクロ流体デバイスとヒト全血を用いたナノ粒子の血管透過性評価

守谷侑美, 小田中美希, 佐々木直樹

日本分析化学会第66年会 9 9 2017

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
細胞集団移動の基質依存性の分析に用いる表面化学・力学特性が制御された光応答基板の開発

岡田佳, 山本翔太, 山口和夫, 佐々木直樹, 中西淳

日本分析化学会第66年会 9 9 2017

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
A membrane-integrated microfluidic device for co-culture analysis International conference

Tomomi HAYASHI, Nanako INOUE, Naoki. SASAKI

RSC Tokyo International Conference 2017 7 9 2017

▶ More details

Language：English Presentation type：Poster presentation

researchmap
Effects of macromolecular crowding on bead-based padlock rolling circle amplification International conference

Chikako KASE, Naoki. SASAKI, Kae. SATO

RSC Tokyo International Conference 2017 7 9 2017

▶ More details

Language：English Presentation type：Poster presentation

researchmap
Evaluation of vascular permeation of nanoparticles by using a membrane-integrated microfluidic device International conference

Yumi MORIYA, Miki ODANAKA, Naoki SASAKI

RSC Tokyo International Conference 2017 7 9 2017

▶ More details

Language：English Presentation type：Poster presentation

researchmap
生体にまねぶバイオ分析 Invited

佐々木直樹

ナノ茶論 19 5 2017

▶ More details

Language：Japanese Presentation type：Public lecture, seminar, tutorial, course, or other speech

researchmap
Organ on a Chipによる薬剤評価 Invited

佐々木直樹

第3回産学医連携シーズマッチングwith東洋大学 16 3 2017

▶ More details

Language：Japanese Presentation type：Public lecture, seminar, tutorial, course, or other speech

researchmap
FABRICATION OF AN EASY-TO-OBSERVE MEMBRANE-INTEGRATED MICROFLUIDIC DEVICE International conference

Satoshi Watanabe, Naoki Sasaki

The 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS2016) 12 10 2016

▶ More details

Language：English Presentation type：Poster presentation

researchmap
表面化学・力学特性が制御された光応答基板を用いる細胞集団移動の分析

岡田佳, 山本翔太, 佐々木直樹, 山口和夫, 中西淳

日本分析化学会第65年会 14 9 2016

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
ドライエッチングによる石英ガラスの深堀マイクロ流路加工の検討

松下和樹, 森川響二朗, 佐々木直樹, 塚原剛彦

化学とマイクロ・ナノシステム学会第34回研究会 6 9 2016

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
Development of photoactivatable substrate with tuned surface chemistry and substrate stiffness as a platform for collective cell migration study International conference

Kei Okada, Shota Yamamoto, Naoki Sasaki, Kazuo Yamaguchi, Jun Nakanishi

2nd International symposium on nanoarchitectonics for mechanobiology 27 7 2016

▶ More details

Language：English Presentation type：Poster presentation

researchmap
無細胞マイクロ微小循環モデルの開発

臼井裕也, 佐々木直樹

第76回分析化学討論会 28 5 2016

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
腫瘍への届きやすさ評価東洋大、マイクロチップ開発

日経産業新聞

2 5 2016

▶ More details

Language：Japanese Presentation type：Media coverage

researchmap
マイクロビーズPadlock/RCA 法における各種分子クラウディング剤の影響

中畑友祐, 佐藤香枝, 佐々木直樹

化学とマイクロ・ナノシステム学会第33回研究会 25 4 2016

▶ More details

Language：Japanese Presentation type：Poster presentation

Venue：東京大学生産技術研究所

researchmap
マイクロビーズPadlock/RCA 法におけるPolyethylene glycol(PEG)の影響

加瀬央子, 佐々木直樹, 佐藤香枝

化学とマイクロ・ナノシステム学会第33回研究会 25 4 2016

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
オンチップ抽出クロマトグラフィーシステムの構築とランタノイド分析

松下和樹, 森川響二朗, 佐々木直樹, 塚原剛彦

化学とマイクロ・ナノシステム学会第33回研究会 25 4 2016

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
腫瘍血管‐間質複合型無細胞マイクロ流体デバイスの開発

臼井裕也, 渡邉学志, 佐々木直樹

日本化学会第96春季年会 24 3 2016

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
多孔膜集積マイクロ流体デバイスによるナノ粒子の透過性分析

土屋公彰, 佐々木直樹

日本化学会第96春季年会 24 3 2016

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
オンチップ抽出クロマトグラフィーによる金属イオン分析システムの開発

松下和樹, 森川響二朗, 佐々木直樹, 塚原剛彦

第1回次世代イニシアティブ廃炉技術カンファレンス 16 3 2016

▶ More details

Language：Japanese

researchmap
Molecular crowding-assisted on-bead rolling circle amplification for single DNA molecule counting International conference

Naoki Sasaki, Yoshitaka Gunji, Kae Sato

Pacifichem 2015 12 2015

▶ More details

Language：English Presentation type：Poster presentation

researchmap
DNAバルジ構造を利用した5-メチルシトシンの電気化学分析

吉田岳史, 佐々木直樹, 栁澤博幸, 栗田僚二, 丹羽修

第5回CSJ化学フェスタ2015 10 2015

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
Single DNA molecules detection by on-bead rolling circle amplification in a crowded environment International conference

Yoshitaka Gunji, Akiho Numata, Kae Sato, Naoki Sasaki

RSC Tokyo International Conference 2015 9 2015

▶ More details

Language：English Presentation type：Poster presentation

researchmap
Alternating current cloud point extraction: the use of ferrocenyl surfactant International conference

Yuya Usui, Naoki Sasaki

RSC Tokyo International Conference 2015 9 2015

▶ More details

Language：English Presentation type：Poster presentation

researchmap
演繹的及び構成的アプローチに基づくマイクロバイオ分析デバイスの開発 Invited

佐々木直樹

日本分析化学会第64年会 9 2015

▶ More details

Language：Japanese Presentation type：Oral presentation (invited, special)

researchmap
Cell-free microfluidic vascular models for nanoDDS Invited

Naoki SASAKI

2nd Asian Symposium for Analytical Sciences (in the 64th Annual Meeting of The Japan Society for Analytical Chemistry) 9 2015

▶ More details

Language：English Presentation type：Oral presentation (invited, special)

researchmap
DNAバルジ構造を利用した5-メチルシトシンの電気化学分析

吉田岳史, 佐々木直樹, 栁澤博幸, 栗田僚二, 丹羽修

第75回分析化学討論会 5 2015

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
分子クラウディングを利用したマイクロビーズPadlock/RCA法の高感度化

郡司良隆, 佐藤香枝, 佐々木直樹

第75回分析化学討論会 5 2015

▶ More details

Language：Japanese Presentation type：Oral presentation (general)

researchmap
Molecular crowding improves single DNA molecules detection by on-bead rolling circle amplification International conference

Yoshitaka Gunji, Kae Sato, Naoki Sasaki

RSC Tokyo International Conference 2014 9 2014

▶ More details

Language：English Presentation type：Poster presentation

researchmap
分子クラウディング環境下でのマイクロビーズPadlock/RCA法による単一DNA検出

青山春樹, 佐藤香枝, 佐々木直樹

化学とマイクロ・ナノシステム学会第２９回研究会 5 2014

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
マイクロチップ交流曇点抽出法の水性二相系への展開

佐々木直樹, 安達尭史

化学とマイクロ・ナノシステム学会第２９回研究会 5 2014

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
分子クラウディングを利用したマイクロビーズPadlock/RCA法の高機能化

青山春樹, 佐藤香枝, 佐々木直樹

第74回分析化学討論会 5 2014

▶ More details

Language：Japanese Presentation type：Oral presentation (general)

researchmap
水性二相系を用いたマイクロチップ交流曇点抽出法の開発

安達尭史, 佐々木直樹

日本化学会第94春季年会 3 2014

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
微小循環マイクロモデルの開発

佐藤美和, 佐々木直樹, 平川聡史, 佐藤香枝

化学とマイクロ・ナノシステム学会第２８回研究会 12 2013

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
マイクロチップを用いたフロー培養法における細胞増殖

佐藤美和, 佐々木直樹, 平川聡史, 佐藤香枝

第33回キャピラリー電気泳動シンポジウム 11 2013

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
マイクロチップ交流曇点抽出法の開発

佐々木直樹

第33回キャピラリー電気泳動シンポジウム 11 2013

▶ More details

Language：Japanese Presentation type：Oral presentation (general)

researchmap
血管・リンパ管マイクロデバイスの構築と特性評価

佐藤美和, 佐々木直樹, 平川聡史, 佐藤香枝

第3回CSJ化学フェスタ2013 10 2013

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
DEVELOPMENT OF AN EX-VIVO LYMPHATIC VASCULAR MODEL International conference

Miwa Sato, Naoki Sasaki, Kiichi Sato, Satoshi Hirakawa, Kae Sato

The 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2013) 10 2013

▶ More details

Language：English Presentation type：Poster presentation

researchmap
CHARACTERIZATION OF NANOPARTICLE PERMEABILITY ON A MEMBRANE-INTEGRATED MICROFLUIDIC DEVICE International conference

Naoki Sasaki, Mariko Tatanou, Yasutaka Anraku, Akihiro Kishimura, Kazunori Kataoka, Kae Sato

The 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2013) 10 2013

▶ More details

Language：English Presentation type：Poster presentation

researchmap
CHARACTERIZATION OF A MICROFLUIDIC IN VITRO MODEL OF LYMPHATIC VESSEL International conference

Miwa Sato, Naoki Sasaki, Satoshi Hirakawa, Kae Sato

RSC Tokyo International Conference 2013 9 2013

▶ More details

Language：English Presentation type：Poster presentation

researchmap
OPTIMIZATION OF MICROFLUIDIC-BASED IN SITU PADLOCK ROLLING CIRCLE AMPLIFICATION FOR MITOCHONDRIAL DNA ANALYSIS International conference

Arisa Kuroda, Naoki Sasaki, Mats Nilsson, Kae Sato

RSC Tokyo International Conference 2013 9 2013

▶ More details

Language：English Presentation type：Poster presentation

researchmap
CHARACTERIZATION OF NANOPARTICLE PERMEABILITY ON MEMBRANE-INTEGRATED MICROFLUIDIC DEVICES International conference

Naoki Sasaki, Mariko Tatanou, Yasutaka Anraku, Akihiro Kishimura, Kazunori Kataoka, Kae Sato

RSC Tokyo International Conference 2013 9 2013

▶ More details

Language：English Presentation type：Poster presentation

researchmap
マイクロ流体デバイスを用いるナノ粒子の透過性評価

佐々木直樹, 多多納麻里子, 安楽泰孝, 岸村顕広, 片岡一則, 城潤一郎, 青木伊知男, 佐藤香枝

日本分析化学会第62年会 9 2013

▶ More details

Language：Japanese Presentation type：Oral presentation (general)

researchmap
血管・リンパ管内皮細胞のマイクロチップ培養

佐藤美和, 佐々木直樹, 平川聡史, 佐藤香枝

化学とマイクロ・ナノシステム学会第27回研究会 5 2013

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
多孔膜集積マイクロ流体デバイスを用いたDDSナノ粒子の透過性評価

佐々木直樹, 多多納麻里子, 安楽泰孝, 岸村顕広, 片岡一則, 佐藤香枝

化学とマイクロ・ナノシステム学会第27回研究会 5 2013

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
分子・細胞・組織分析のためのマイクロ流体デバイス Invited

佐々木直樹

集積マイクロシステム研究センター研究会 10 2012

▶ More details

Language：Japanese Presentation type：Oral presentation (invited, special)

researchmap
光架橋反応を利用する細胞パターニングと細胞内DNA分析への応用 Invited

佐々木直樹, 井須安里, 石井怜奈, 佐藤香枝

第２６回化学とマイクロ・ナノシステム研究会 10 2012

▶ More details

Language：Japanese Presentation type：Oral presentation (invited, special)

researchmap
Mechanistic characterization of alternating current cloud point extraction in a microchannel: extraction under physiological temperature International conference

Naoki SASAKI, Azusa TAKEMURA, Kae SATO

The 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS2012) 10 2012

▶ More details

Language：English Presentation type：Poster presentation

researchmap
Photo-immobilization of cells for in situ DNA analysis International conference

Naoki SASAKI, Anri ISU, Reina ISHII, Kae SATO

The 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS2012) 10 2012

▶ More details

Language：English Presentation type：Poster presentation

researchmap
MICROFLUIDIC DEVICES FOR PERMEABILITY ASSAYS OF LYMPHATIC ENDOTHELIAL CELLS International conference

Miwa SATO, Naoki SASAKI, Kae SATO

RSC Tokyo International Conference 2012 9 2012

▶ More details

Language：English Presentation type：Poster presentation

researchmap
MICROCHIP-BASED IN-SITU PADLOCK/ROLLING CIRCLE AMPLIFICATION (MICRO-RCA) SYSTEM FOR SINGLE DNA COUNTING IN A CELL International conference

Arisa KURODA, Naoki SASAKI, Kae SATO

RSC Tokyo International Conference 2012 9 2012

▶ More details

Language：English Presentation type：Poster presentation

researchmap
PHOTOCROSSLINKING OF CELLS TO A GLASS SUBSTRATE FOR IN SITU DNA ANALYSIS International conference

Naoki SASAKI, Eri YOSHIDA, Anri ISU, Reina ISHII, Kae SATO

RSC Tokyo International Conference 2012 9 2012

▶ More details

Language：English Presentation type：Poster presentation

researchmap
創薬研究のためのバイオマイクロ流体デバイス Invited

佐々木直樹

第23回新薬創製談話会 9 2012

▶ More details

Language：Japanese Presentation type：Oral presentation (invited, special)

researchmap
光架橋反応を利用したガラス基板への細胞固定化法の開発

佐々木直樹, 井須安里, 佐藤香枝

第72回分析化学討論会 5 2012

▶ More details

Language：Japanese Presentation type：Oral presentation (general)

researchmap
手のひらサイズのマイクロチップ細胞培養システム

佐々木直樹, 新城美佳, 平川聡史, 西中正弘, 田中陽, 馬渡和真, 北森武彦, 佐藤香枝

第25回化学とマイクロ・ナノシステム研究会 5 2012

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
光架橋反応を利用したガラス基板への細胞固定化と細胞内DNA分析への応用

佐々木直樹, 井須安里, 石井怜奈, 佐藤香枝

第25回化学とマイクロ・ナノシステム研究会 5 2012

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
微小循環マイクロモデルの開発 Invited

佐藤香枝, 佐々木直樹

第89回日本生理学会大会 3 2012

▶ More details

Language：Japanese Presentation type：Oral presentation (invited, special)

researchmap
細胞内Padlock/RCA のためのマイクロチップ送液システムの開発

第32回キャピラリー電気泳動シンポジウム 2012

▶ More details

researchmap
リンパ管内皮細胞のマイクロデバイス培養と細胞間接着分子の観察

第2回CSJ化学フェスタ 2012

▶ More details

Presentation type：Poster presentation

researchmap
マイクロチップを用いた細胞内Padlock/RCA法の開発

第2回CSJ化学フェスタ 2012

▶ More details

Presentation type：Poster presentation

researchmap
マイクロチップ送液システムを用いたPadlock/RCA法によるDNA分析

日本分析化学会第61年会 2012

▶ More details

researchmap
交流動電現象を利用するマイクロ流体デバイスの開発とバイオ分析への応用 Invited

佐々木直樹

日本女子大学理学セミナー 10 2011

▶ More details

Language：Japanese Presentation type：Oral presentation (invited, special)

researchmap
Development of a microfluidic southern hybridization analysis system using microbeads International conference

Kae SATO, Mami NISHIKAWA, Naoki SASAKI, Kiichi SATO

The 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS2011) 10 2011

▶ More details

Language：English Presentation type：Poster presentation

researchmap
Mechanistic investigation of alternating current cloud point extraction in a microchannel International conference

Naoki SASAKI, Azusa TAKEMURA, Kae SATO

The 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS2011) 10 2011

▶ More details

Language：English Presentation type：Poster presentation

researchmap
Counting single DNA molecule by on-bead rolling circle amplification for quantitative analyses International conference

Reina ISHII, Naoki SASAKI, Kiichi SATO, Kazuma MAWATARI, Mats NILSSON, Takehiko KITAMORI, Kae SATO

hemistry and Life Sciences (MicroTAS2011) 10 2011

▶ More details

Language：English Presentation type：Poster presentation

researchmap
交流曇点抽出法による生体膜分子のオンチップ濃縮機構の解析

佐々木直樹, 竹村梓, 佐藤香枝

日本分析化学会第60年会 9 2011

▶ More details

Presentation type：Oral presentation (general)

researchmap
交流曇点抽出法によるオンチップ生体膜分子濃縮の特性解析

佐々木直樹, 竹村梓, 佐藤香枝

第23回化学とマイクロ・ナノシステム研究会 6 2011

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
Single DNA Molecule Detection by On-Bead Rolling Circle Amplification for Efficient Detection International conference

Naoki SASAKI, Reina ISHII, Yuri KITAMURA, Kiichi SATO, Kazuma MAWATARI, Mats NILSSON, Takehiko KITAMORI, Kae SATO

IUPAC International Congress on Analytical Sciences 2011 5 2011

▶ More details

Language：English Presentation type：Poster presentation

researchmap
Experimental characterization of alternating current cloud point extraction International conference

Naoki SASAKI, Azusa TAKEMURA, Kae SATO

IUPAC International Congress on Analytical Sciences 2011 5 2011

▶ More details

Language：English Presentation type：Poster presentation

researchmap
交流曇点抽出法による生体膜分子のオンチップ濃縮

佐々木直樹, 竹村梓, 佐藤香枝

第4回ナノバイオ若手ネットワーキングシンポジウム 3 2011

▶ More details

Language：Japanese Presentation type：Oral presentation (general)

researchmap
交流動電現象を利用するオンチップバイオ分析 Invited

佐々木直樹

日本女子大学理科縦の会 2 2011

▶ More details

Language：Japanese Presentation type：Oral presentation (invited, special)

researchmap
マイクロ流体デバイスを用いた血管内皮細胞の培養

第1回CSJ化学フェスタ 2011

▶ More details

Presentation type：Poster presentation

researchmap
マイクロビーズ電気泳動によるサザンハイブリダイゼーション法の開発

第23回化学とマイクロ・ナノシステム研究会 2011

▶ More details

Presentation type：Poster presentation

researchmap
マイクロペリスタリックポンプを用いたマイクロチップ細胞培養

第23回化学とマイクロ・ナノシステム研究会 2011

▶ More details

Presentation type：Poster presentation

researchmap
マイクロビーズを用いたPadlock/RCA法の開発

第23回化学とマイクロ・ナノシステム研究会 2011

▶ More details

Presentation type：Poster presentation

researchmap
Alternating current cloud point extraction on a microfluidic chip for preconcentration of membrane-associated biomolecules International conference

Naoki SASAKI, Kazuo HOSOKAWA, Mizuo MAEDA

2010 International Chemical Congress of Pacific Basin Societies (Pacifichem2010) 12 2010

▶ More details

Language：English Presentation type：Poster presentation

researchmap
流れを利用する異種細胞配置・融合用マイクロ流路のアレイ化

佐々木直樹, 森崎良, Jiansheng Gong, 細川和生, 伊藤嘉浩, 前田瑞夫

第22回化学とマイクロ・ナノシステム研究会 11 2010

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
Single DNA molecule detection by on-bead rolling circle amplification using microchip for efficient detection International conference

Kae SATO, Yuri KITAMURA, Naoki SASAKI, Kiichi SATO, Kazuma MAWATARI, Mats NILSSON, Takehiko KITAMORI

The 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS2010) 10 2010

▶ More details

Language：English Presentation type：Poster presentation

researchmap
Pairing and fusion of heterotypic cells in a microchannel International conference

Naoki SASAKI, Jiangsheng GONG, Kazuo HOSOKAWA, Mizuo MAEDA, Yoshihiro ITO

The 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS2010) 10 2010

▶ More details

Language：English Presentation type：Oral presentation (general)

researchmap
マイクロビーズを用いたPadlock/RCA法の開発

北村友理, 佐々木直樹, 佐藤香枝

第21回化学とマイクロ・ナノシステム研究会 6 2010

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
マイクロ流路内異種細胞配置・融合法の開発

佐々木直樹, Jiansheng Gong, 細川和生, 前田瑞夫, 伊藤嘉浩

第21回化学とマイクロ・ナノシステム研究会 6 2010

▶ More details

Language：Japanese Presentation type：Poster presentation

researchmap
マイクロ流体デバイスを用いるES細胞－体細胞融合法の開発

第3回ナノバイオ若手ネットワーキングシンポジウム 2010

▶ More details

researchmap
細胞融合実験用マイクロ流体チップの開発

日本化学会第4回関東支部大会 2010

▶ More details

Presentation type：Poster presentation

researchmap
マイクロビーズPadlock/RCA法による微量DNA分析

東京コンファレンス2010 2010

▶ More details

Presentation type：Poster presentation

researchmap
交流動電現象のオンチップバイオ分析への応用 Invited

佐々木直樹

第4回バイオ医工学シンポジウム 3 2009

▶ More details

Language：Japanese Presentation type：Oral presentation (invited, special)

researchmap
交流動電現象を利用するオンチップ曇点抽出

東京コンファレンス2009 2009

▶ More details

Presentation type：Poster presentation

researchmap
交流動電相分離とその濃縮操作への応用（３）：流体挙動の解析

第19回化学とマイクロ・ナノシステム研究会 2009

▶ More details

Presentation type：Poster presentation

researchmap
Analysis of fluid motion in alternating current cloud point extraction

The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2009

▶ More details

Presentation type：Poster presentation

researchmap
Analysis of fluid motion in alternating current cloud point extraction

The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2009

▶ More details

Presentation type：Poster presentation

researchmap
交流動電相分離とその濃縮操作への応用（２）：濃縮機構の検討

日本分析化学会第57年会 2008

▶ More details

researchmap
交流動電相分離とその濃縮操作への応用

第17回化学とマイクロ・ナノシステム研究会 2008

▶ More details

Presentation type：Poster presentation

researchmap
AC electrokinetic phase separation, focusing and concentration in microchannel

The 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2008

▶ More details

Presentation type：Poster presentation

researchmap
AC electrokinetic phase separation, focusing and concentration in microchannel

The 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2008

▶ More details

Presentation type：Poster presentation

researchmap
交流熱動電流を利用した高速マイクロミキサー

第15回化学とマイクロ・ナノシステム研究会 2007

▶ More details

Presentation type：Poster presentation

researchmap
Rapid mixing by AC electrothermal flow

The 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2007

▶ More details

Presentation type：Poster presentation

researchmap
Rapid mixing by AC electrothermal flow

The 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2007

▶ More details

Presentation type：Poster presentation

researchmap
交流電気浸透を利用した高速マイクロミキサー（４）：溶媒依存性の検討

第13回化学とマイクロ・ナノシステム研究会 2006

▶ More details

Presentation type：Poster presentation

researchmap
交流動電現象のマイクロ化学プロセスへの応用

日本分析化学会第55年会 2006

▶ More details

researchmap
Fluid Mixing by AC Electroosmosis in Microchannel

International Electrokinetics Conference 2006

▶ More details

researchmap
Performance Evaluations of Fluid Mixing by AC Electroosmosis in Microchannel

International Electrokinetics Conference 2006

▶ More details

Presentation type：Poster presentation

researchmap
AC electroosmotic micromixer: viscosity and ionic strength dependence of mixing time

The 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2006

▶ More details

Presentation type：Poster presentation

researchmap
Fluid Mixing by AC Electroosmosis in Microchannel

International Electrokinetics Conference 2006

▶ More details

researchmap
Performance Evaluations of Fluid Mixing by AC Electroosmosis in Microchannel

International Electrokinetics Conference 2006

▶ More details

Presentation type：Poster presentation

researchmap
AC electroosmotic micromixer: viscosity and ionic strength dependence of mixing time

The 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2006

▶ More details

Presentation type：Poster presentation

researchmap
AC Electroosmotic Mixer for Rapid Mixing in Microchannel on Chip

Pacifichem 2005 2005

▶ More details

researchmap
Rapid mixing based on AC electroosmosis in microchannel

The 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2005

▶ More details

Presentation type：Poster presentation

researchmap
AC Electroosmotic Mixer for Rapid Mixing in Microchannel on Chip

Pacifichem 2005 2005

▶ More details

researchmap
Rapid mixing based on AC electroosmosis in microchannel

The 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2005

▶ More details

Presentation type：Poster presentation

researchmap

▼display all

Teaching Experience

2025 - Present

Analytical Chemistry 3 （ Rikkyo University ）

▶ More details

researchmap
9 2022 - Present

分析化学II （日本女子大学）

▶ More details

researchmap
2022 - Present

自然科学の探求（立教大学）

▶ More details

researchmap
2020 - Present

化学実験C （立教大学）

▶ More details

researchmap
2020 - Present

化学実験B （立教大学）

▶ More details

researchmap
2020 - Present

化学実験A （立教大学）

▶ More details

researchmap
2020 - Present

化学の最前線（立教大学）

▶ More details

researchmap
2020 - Present

分析化学応用特論１（立教大学）

▶ More details

researchmap
2020 - Present

分析化学１（立教大学）

▶ More details

researchmap
9 2023 - 3 2025

科学英語（立教大学）

▶ More details

researchmap
2021

専門化学実験III （お茶の水女子大学）

▶ More details

researchmap
4 2013 - 3 2020

先端化学（東洋大学）

▶ More details

researchmap
4 2013 - 3 2020

物理化学II （東洋大学）

▶ More details

researchmap
4 2013 - 3 2020

物理化学I （東洋大学）

▶ More details

researchmap
4 2013 - 3 2020

化学実験（東洋大学）

▶ More details

researchmap
4 2018 - 3 2019

物理化学III （東洋大学）

▶ More details

researchmap
4 2016 - 3 2019

ナノサイエンス（東洋大学）

▶ More details

researchmap
4 2013 - 3 2018

安全化学（東洋大学）

▶ More details

researchmap
4 2013 - 3 2016

化学II （東洋大学）

▶ More details

researchmap
4 2010 - 3 2013

物理化学実験（日本女子大学）

▶ More details

researchmap
4 2010 - 3 2013

化学概論実験（日本女子大学）

▶ More details

researchmap

▼display all

Professional Memberships

THE CHEMICAL SOCIETY OF JAPAN

▶ More details

researchmap
THE SOCIETY OF POLYMER SCIENCE, JAPAN

▶ More details

researchmap
THE SOCIETY FOR CHEMISTRY AND MICRO-NANO SYSTEMS

▶ More details

researchmap
THE JAPAN SOCIETY FOR ANALYTICAL CHEMISTRY

▶ More details

researchmap

Research Projects

非腫瘍細胞を有するマイクロ腫瘍組織モデルの構築

日本学術振興会科学研究費助成事業

佐々木直樹, 岸村顕広

▶ More details

4 2023 - 3 2026

Grant number：23K04559

Grant amount：\4680000 （ Direct Cost: \3600000 、 Indirect Cost：\1080000 ）

researchmap
Microfluidic tumor model for nanomedicine development

Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research

Sasaki Naoki

▶ More details

4 2019 - 3 2022

Grant number：19K05236

Grant amount：\4420000 （ Direct Cost: \3400000 、 Indirect Cost：\1020000 ）

Nanomedicines are believed to be capable of tumor-selective drug delivery, but their clinical application has not progressed. In this study, we aimed to construct a microfluidic tumor model that reflects the structure and characteristics of human tumor tissue and apply it to the evaluation of nanomedicines. Vascular endothelial cells, tumor cells, and macrophages were incorporated into the device, and the permeability and cellular uptake of nanoparticles were evaluated. Microfluidic devices suitable for microscopic observation were fabricated, and the effects of various conditions on the dynamics of nanoparticles were clarified.

researchmap
White box testing of nanomedicines on a microfluidic device

Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research

Sasaki Naoki

▶ More details

4 2015 - 3 2018

Grant number：15K04640

Grant amount：\4940000 （ Direct Cost: \3800000 、 Indirect Cost：\1140000 ）

Nanoparticles have been widely utilized to deliver drugs from blood vessels to tumor tissues. In this study, we developed a microfluidic device to clarify nanoparticle characteristics required for efficient drug delivery. A consumer laser cutter was employed to fabricate the device. Tumor cells and vascular endothelial cells were co-cultured on a membrane-integrated microfluidic device. Permeation of nanoparticles through the endothelial monolayer increased in the presence of tumor cells.

researchmap
Rapid, sensitive, and on-site detection of bacteria using DNA amplidication on an electrode-integrated microfluidic device

Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research

SASAKI Naoki

▶ More details

4 2013 - 3 2015

Grant number：25790037

Grant amount：\4420000 （ Direct Cost: \3400000 、 Indirect Cost：\1020000 ）

This project is a proof-of concept study of rapid, sensitive, and on-site detection of bacteria using DNA amplidication on an electrode-integrated microfluidic device. Concentration of samples under alternating electric fields in a microfluidic channel was demonstrated. DNA detection by rolling circle amplification (RCA) was also demonstrated. Poly(ethylene glycol) (PEG) was used to facilitate RCA by molecular crowding effects. The number of RCA products increased in the presence of PEG.

researchmap
Microfluidic device for stem cell communication analysis

Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research

SASAKI Naoki

▶ More details

2009 - 2010

Grant number：21710131

Grant amount：\4810000 （ Direct Cost: \3700000 、 Indirect Cost：\1110000 ）

Stem cells can replicate themselves and differentiate into various types of somatic cells. It is highly important to clarify such mechanisms from a scientific point of view and for the application in the area of regenerative medicine. We have developed microfluidic devices to analyze the communication between stem cells. Controlled pairing of embryonic stem cells with somatic cells has been demonstrated. An arrayed microfluidic device which has multiple microchannels has enabled high throughput operations.

researchmap
微細加工技術を駆使した細胞質注入による体細胞リプログラミング法の確立

日本学術振興会科学研究費助成事業

伊藤嘉浩, 細川和生, 佐々木直樹

▶ More details

2009 - 2009

Grant number：21650122

Grant amount：\3200000 （ Direct Cost: \3200000 ）

京都大学の多田らによって2001年に、体細胞とES細胞を細胞融合する手法でも体細胞はリプログラミングされることが、マウスを使って報告されると(Curr.Biol., 2001, 11, 1553-1158)、2005年にはハーバード大学でヒトES細胞を使っての成功が報じられた(Science, 2005, 309, 1369-1373)。しかし、この方法で作成する細胞は4倍体で、正常2倍体とは異なる。山中らはこの報告に触発され、ES細胞中にある遺伝子の注入による体細胞のリプログラミングを実現した。しかし、遺伝子導入のためにレトロウイルスを用いており、遺伝子治療での課題は未解決のままである。
そこで、本研究では、体細胞とES細胞を融合させ、細胞質交換はあるものの核の移動が起こらない数マイクロメートルの孔を介して細胞を対峙させ、細胞融合を行い2倍体の体細胞由来ES様細胞の構築を目指した体細胞とES細胞を所定の位置にポジショニングするためのマイクロ流路を組み込んだマイクロデバイスを設計し、作成した。ES細胞と体細胞の融合には、HVJエンベロープを用いた。細胞融合を行ったところ、20分後にはES細胞から体細胞へグリーン・フルオレセンス・センスプロテイン(GFP)が移動し、両者の細胞核はそのまま移動しいことが蛍光顕微鏡で確認することができ、当初計画したデバイスが作成できた。さらにマルチ流路型デバイスも作成し、同時に32か所で細胞融合の試行が可能となった。ただし、本研究期間内だけでは、この細胞質の移動による体細胞のリプログラミングまでは観察できなかった。

researchmap

▼display all

Industrial property rights

細胞遊走アッセイデバイス

佐々木直樹

▶ More details

Application no：特願2018-157278 Date applied：24 8 2018

Announcement no：特開2020-028270 Date announced：27 2 2020

researchmap
膜組み込みマイクロ流体デバイスの製造方法

佐々木直樹

▶ More details

Application no：特願2018-157270 Date applied：24 8 2018

Announcement no：特開2020-028962 Date announced：27 2 2020

researchmap
光架橋反応を利用したガラス基板への細胞固定化法

佐藤香枝, 佐々木直樹

▶ More details

Application no：特願2012-83371 Date applied：31 3 2012

Announcement no：特開2013-212059 Date announced：17 10 2013

researchmap
マイクロミキサーおよび流体の撹拌方法並びに流体の混合方法

北森武彦, 金幸夫, 佐々木直樹

▶ More details

Application no：特願2006-243584 Date applied：8 9 2006

Announcement no：特開2008-062190 Date announced：21 3 2008

researchmap
流体混合装置

北森武彦, 金幸夫, 佐々木直樹

▶ More details

Application no：特願2005-148720 Date applied：20 5 2005

Patent/Registration no：特許4590558 Date issued：1 12 2010

researchmap
マイクロミキサーおよび流体の撹拌方法並びに流体の混合方法

北森武彦, 金幸夫, 佐々木直樹

▶ More details

Application no：特願2005-148719 Date applied：20 5 2005

Patent/Registration no：特許4590557 Date issued：1 12 2010

researchmap

▼display all